TOFA ( RMI14514; MDL14514)
Catalog No: 20376
CAS Number: 54857-86-2
Purity: ≧98.0%
TOFA ( RMI14514; MDL14514) is an allosteric inhibitor of acetyl-CoA carboxylase-α (ACCA). Inside the cell, TOFA is converted to TOFyl-CoA (5-tetradecyloxy-2-furoyl-CoA), exerting an allosteric inhibition on ACCA. TOFA blocks fatty acid synthesis and induces cell death in a dose-dependent manner.
For research use only. We do not sell to patients.
Chemical Information
| Name | TOFA ( RMI14514; MDL14514) |
|---|---|
| Iupac Chemical Name | 5-(TETRADECYLOXY)-2-FUROIC ACID |
| Synonyms | TOFA ; RMI14514 ; MDL14514 |
| Molecular Formula | C19H32O4 |
| Molecular Weight | 324.45 |
| Smile | O=C(O)C1=CC=C(OCCCCCCCCCCCCCC)O1 |
| InChiKey | CZRCFAOMWRAFIC-UHFFFAOYSA-N |
| InChi | InChI=1S/C19H32O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-16-22-18-15-14-17(23-18)19(20)21/h14-15H,2-13,16H2,1H3,(H,20,21) |
| CAS Number | 54857-86-2 |
| Related CAS | 54857-86-2 |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Off-white solid |
|---|---|
| Purity | ≧98.0% |
| Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
| Solubility | Soluble in DMSO |
| Handling | Refer to MSDS |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code | 2934200090 |
Coming soon.
| Targets | TOFA ( RMI14514; MDL14514) is an allosteric inhibitor of acetyl-CoA carboxylase-α (ACCA). |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
