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AST487

Catalog No: 186158
CAS Number: 630124-46-8
Purity: >98%

AST487, also known as NVP- AST487, is a RET kinase inhibitor/FLT3 inhibitor.

For research use only. We do not sell to patients.

Chemical Information

NameAST487
Iupac Chemical Name1-(4-((4-ethylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-(4-((6-(methylamino)pyrimidin-4-yl)oxy)phenyl)urea
SynonymsNVPAST487; AST 487; AST487; AST-487.
Molecular FormulaC26H30F3N7O2
Molecular Weight529.56
SmileO=C(NC1=CC=C(OC2=NC=NC(NC)=C2)C=C1)NC3=CC=C(CN4CCN(CC)CC4)C(C(F)(F)F)=C3
InChiKeyODPGGGTTYSGTGO-UHFFFAOYSA-N
InChiInChI=1S/C26H30F3N7O2/c1-3-35-10-12-36(13-11-35)16-18-4-5-20(14-22(18)26(27,28)29)34-25(37)33-19-6-8-21(9-7-19)38-24-15-23(30-2)31-17-32-24/h4-9,14-15,17H,3,10-13,16H2,1-2H3,(H,30,31,32)(H2,33,34,37)
CAS Number630124-46-8
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Ordering Information

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FormulationOff-white solid to white solid
Purity>98%
StorageDry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
SolubilitySoluble in DMSO
Handling
Shipping ConditionShipped under ambient temperature
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

186158 - AST487 | CAS 630124-46-8

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