AT7867
Catalog No: 161009021
CAS Number: 857531-00-1 (free base); 1431697-86-7 (2HCl)
Purity: 98% by HPLC
This ATP-competitive small molecule potently inhibits both AKT and p70S6K activity at the cellular level, as measured by inhibition of GSK3beta and S6 ribosomal protein phosphorylation, and also causes growth inhibition in a range of human cancer cell lines as a single agent.
For research use only. We do not sell to patients.
Chemical Information
| Name | AT7867 |
|---|---|
| Iupac Chemical Name | 4-(4-(1H-pyrazol-4-yl)phenyl)-4-(4-chlorophenyl)piperidine |
| Synonyms | AT7867; AT 7867; AT-7867; AT7867 HCl; AT7867 dihydrochloride. AT7867 hydrochloride. |
| Molecular Formula | C20H20ClN3 |
| Molecular Weight | 337.8459 |
| Smile | N1N=CC(=C1)C1=CC=C(C=C1)C1(CCNCC1)C1=CC=C(C=C1)Cl |
| InChiKey | LZMOSYUFVYJEPY-UHFFFAOYSA-N |
| InChi | InChI=1S/C20H20ClN3/c21-19-7-5-18(6-8-19)20(9-11-22-12-10-20)17-3-1-15(2-4-17)16-13-23-24-14-16/h1-8,13-14,22H,9-12H2,(H,23,24) |
| CAS Number | 857531-00-1 (free base); 1431697-86-7 (2HCl) |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | 98% by HPLC |
| Storage | -20 ºC for 3 years |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
