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AZD1152-HQPA Catalog No : 51904

Chemical Information

Product NameAZD1152-HQPA
Iupac Chemical Name2-(5-(7-(3-(ethyl(2-hydroxyethyl)amino)propoxy)quinazolin-4-ylamino)-1H-pyrazol-3-yl)-N-(3-fluorophenyl)acetamide 
SynonymsAZD1152-HQPA 
Molecular FormulaC26H30FN7O3 
Molecular Weight507.56 
SmileC(C)N(CCCOC1=CC=C2C(=NC=NC2=C1)NC1=CC(=NN1)CC(=O)NC1=CC(=CC=C1)F)CCO
InChiKeyQYZOGCMHVIGURT-UHFFFAOYSA-N
InChiInChI=1S/C26H30FN7O3/c1-2-34(10-11-35)9-4-12-37-21-7-8-22-23(16-21)28-17-29-26(22)31-24-14-20(32-33-24)15-25(36)30-19-6-3-5-18(27)13-19/h3,5-8,13-14,16-17,35H,2,4,9-12,15H2,1H3,(H,30,36)(H2,28,29,31,32,33)
Cas722544-51-6

Technical Data

Appearanceoff-white solid 
Purity98% 
Solubility5mg/ml in DMSO 
Storage3 years -20ºCpowder 
Shipping ConditionShipped under ambient temperature 
Quality control

Description

Barasertib (AZD1152-HQPA) is a highly selective Aurora B inhibitor with IC50 of 0.37 nM, ~3700 fold more selective for Aurora B over Aurora A. Phase 1. 

Chemical Structure

51904 - AZD1152-HQPA | CAS 722544-51-6

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