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AZD4205

Catalog No: 20178710
CAS Number: 2091134-35-7
Purity: 98.0% 

AZD4205 is a highly potent JAK1-selective kinase inhibitor with excellent preclinical pharmacokinetics with potential for further clinical development. 

For research use only. We do not sell to patients.

Chemical Information

NameAZD4205
Iupac Chemical Name(R)-2-((R)-3,4-dimethylpiperazin-1-yl)-N-(3-(5-fluoro-2-((3-methoxy-1-methyl-1H-pyrazol-4-yl)amino)pyrimidin-4-yl)-1H-indol-7-yl)propanamide 
SynonymsAZD4205;AZD-4205;AZD 4205 
Molecular FormulaC26H32FN9O2 
Molecular Weight521.6014 
SmileC[C@@H]1CN(CCN1C)[C@@H](C(=O)NC=1C=CC=C2C(=CNC12)C1=NC(=NC=C1F)NC=1C(=NN(C1)C)OC)C
InChiKeyHKMXSVZYKLTDAP-HZPDHXFCSA-N
InChiInChI=1S/C26H32FN9O2/c1-15-13-36(10-9-34(15)3)16(2)24(37)30-20-8-6-7-17-18(11-28-23(17)20)22-19(27)12-29-26(32-22)31-21-14-35(4)33-25(21)38-5/h6-8,11-12,14-16,28H,9-10,13H2,1-5H3,(H,30,37)(H,29,31,32)/t15-,16-/m1/s1
CAS Number2091134-35-7
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Ordering Information

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Formulationoff-white solid 
Purity98.0% 
Storage-20 ºC for 3 years 
SolubilitySoluble in DMSO 
Handling
Shipping ConditionShipped under ambient temperature 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

20178710 - AZD4205 | CAS 2091134-35-7

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