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Acrizanib Catalog No : 184181

Chemical Information

Product NameAcrizanib
Iupac Chemical Name5-({6-[(methylamino)methyl]pyrimidin-4-yl}oxy)-N-[1-methyl-5-(trifluoromethyl)-1H-pyrazol-3-yl]-1H-indole-1-carboxamide
SynonymsAcrizanib; LHA510; LHA 510; LHA-510.
Molecular FormulaC20H18F3N7O2
Molecular Weight445.4062
SmileO=C(N1C=CC2=C1C=CC(OC3=NC=NC(CNC)=C3)=C2)NC4=NN(C)C(C(F)(F)F)=C4
InChiKeyXPIHPLVWOUDMPF-UHFFFAOYSA-N
InChiInChI=1S/C20H18F3N7O2/c1-24-10-13-8-18(26-11-25-13)32-14-3-4-15-12(7-14)5-6-30(15)19(31)27-17-9-16(20(21,22)23)29(2)28-17/h3-9,11,24H,10H2,1-2H3,(H,27,28,31)
Cas1229453-99-9

Technical Data

AppearanceOff-white solid to white solid
Purity>98%
SolubilitySoluble in DMSO
StorageDry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Shipping ConditionShipped under ambient temperature
Quality control

Description

Acrizanib, also known as LHA510, is a potent and selective angiogenesis inhibitor and VEGFR‑2 Inhibitor.

Chemical Structure

184181 - Acrizanib  | CAS 1229453-99-9

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