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BI-D1870

Catalog No: 122914
CAS Number: 501437-28-1
Purity: 98% 

BI-D1870 is an ATP-competitive inhibitor of S6 ribosome for RSK1/2/3/4 with IC50 of 31 nM/24 nM/18 nM/15 nM, respectively; 10- to 100-fold selectivity for RSK than MST2, GSK-3, MARK3, CK1 and Aurora B. BI-D1870 also has a Kd value of 3.5 uM for BRD4. 

For research use only. We do not sell to patients.

Chemical Information

NameBI-D1870
Iupac Chemical Name2-(3,5-difluoro-4-hydroxyanilino)-5,7-dimethyl-8-(3-methylbutyl)-7H-pteridin-6-one 
SynonymsBI-D 1870 
Molecular FormulaC19H23F2N5O2 
Molecular Weight391.415 
SmileCC1C(=O)N(C2=CN=C(N=C2N1CCC(C)C)NC3=CC(=C(C(=C3)F)O)F)C
InChiKeyDTEKTGDVSARYDS-UHFFFAOYSA-N
InChiInChI=1S/C19H23F2N5O2/c1-10(2)5-6-26-11(3)18(28)25(4)15-9-22-19(24-17(15)26)23-12-7-13(20)16(27)14(21)8-12/h7-11,27H,5-6H2,1-4H3,(H,22,23,24)
CAS Number501437-28-1
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Ordering Information

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FormulationSolid powder 
Purity98% 
Storage-20 ºC for 3 years 
SolubilitySoluble in DMSO 
Handling
Shipping ConditionShipped under ambient temperature 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

122914 - BI-D1870 | CAS 501437-28-1

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