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Elvitegravir(GS-9137) Catalog No : 52022

Chemical Information

Product NameElvitegravir(GS-9137)
Iupac Chemical Name(S)-6-(3-chloro-2-fluorobenzyl)-1-(1-hydroxy-3-methylbutan-2-yl)-7-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid 
SynonymsJTK-303 
Molecular FormulaC23H23ClFNO5 
Molecular Weight447.88 
SmileClC=1C(=C(CC=2C=C3C(C(=CN(C3=CC2OC)[C@H](CO)C(C)C)C(=O)O)=O)C=CC1)F
InChiKeyJUZYLCPPVHEVSV-LJQANCHMSA-N
InChiInChI=1S/C23H23ClFNO5/c1-12(2)19(11-27)26-10-16(23(29)30)22(28)15-8-14(20(31-3)9-18(15)26)7-13-5-4-6-17(24)21(13)25/h4-6,8-10,12,19,27H,7,11H2,1-3H3,(H,29,30)/t19-/m1/s1
Cas697761-98-1

Technical Data

Appearanceoff-white solid 
Purity98% 
Solubility5mg/ml in DMSO 
Storage3 years -20ºCpowder 6 months-80ºCin solvent 
Shipping ConditionShipped under ambient temperature 
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Description

Elvitegravir (EVG, formerly GS-9137) is an integrase inhibitor used to treat HIV infection.It was developed by the pharmaceutical company Gilead Sciences, which licensed EVG from Japan Tobacco in March 2008. The drug gained approval by the U.S. FDA on August 27, 2012 for use in adult patients starting HIV treatment for the first time as part of the fixed dose combination known as Stribild.

 

Chemical Structure

52022 - Elvitegravir(GS-9137) | CAS 697761-98-1

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