+0086-27-59253327 sales@sun-shinechem.com

Emricasan(IDN6556,PF03491390) Catalog No : 16071024

Chemical Information

Product NameEmricasan(IDN6556,PF03491390)
Iupac Chemical Name(S)-3-((S)-2-(2-((2-(tert-butyl)phenyl)amino)-2-oxoacetamido)propanamido)-4-oxo-5-(2,3,5,6-tetrafluorophenoxy)pentanoic acid 
SynonymsIDN-6556;IDN6556;PF 03491390;PF-03491390 
Molecular FormulaC26H27F4N3O7 
Molecular Weight569.51 
SmileC(C)(C)(C)C1=C(C=CC=C1)NC(C(=O)N[C@H](C(=O)N[C@@H](CC(=O)O)C(COC1=C(C(=CC(=C1F)F)F)F)=O)C)=O
InChiKeySCVHJVCATBPIHN-SJCJKPOMSA-N
InChiInChI=1S/C26H27F4N3O7/c1-12(31-24(38)25(39)32-16-8-6-5-7-13(16)26(2,3)4)23(37)33-17(10-19(35)36)18(34)11-40-22-20(29)14(27)9-15(28)21(22)30/h5-9,12,17H,10-11H2,1-4H3,(H,31,38)(H,32,39)(H,33,37)(H,35,36)/t12-,17-/m0/s1
Cas254750-02-2

Technical Data

AppearanceOff-white powder 
Purity98% by HPLC 
SolubilitySoluble in DMSO 
Storage-20 ºC for 3 years 
Shipping ConditionShipped under ambient temperature 
Quality control

Description

Emricasan, also known as IDN 6556 and PF 03491390, is a first-in-class caspase inhibitor in clinical trials for the treatment of liver diseases. IDN-6556 has marked efficacy in models of liver disease after oral administration and thus, is an excellent candidate for the treatment of liver diseases characterized by excessive apoptosis. IDN-6556 appears to be a feasible therapeutic agent against ischemia-reperfusion injury in liver transplantation. (Last updated: 7/7/2016).

Synonym: IDN-6556; IDN6556; IDN 6556; PF 03491390; PF-03491390; PF03491390; Emricasan.

 

Chemical Structure

16071024 - Emricasan(IDN6556,PF03491390) | CAS 254750-02-2

Package

SizePrice

Quick Order

Change

Contact Us