Entospletinib (GS-9973)
Catalog No: 16062803
CAS Number: 1229208-44-9
Purity: 98% by HPLC
Entospletinib, also known as GS-9973, is a highly selective and orally efficacious Syk inhibitor which is currently undergoing clinical evaluation for autoimmune and oncology indications. In Phase II clinical trials, Entospletinib demonstrates clinical activity in subjects with relapsed or refractory CLL with acceptable toxicity.
For research use only. We do not sell to patients.
Chemical Information
| Name | Entospletinib (GS-9973) |
|---|---|
| Iupac Chemical Name | 6-(1H-indazol-6-yl)-N-(4-morpholinophenyl)imidazo[1,2-a]pyrazin-8-amine |
| Synonyms | Entospletinib; GS9973; GS 9973; GS-9973. |
| Molecular Formula | C23H21N7O |
| Molecular Weight | 411.46 |
| Smile | N1N=CC2=CC=C(C=C12)C=1N=C(C=2N(C1)C=CN2)NC2=CC=C(C=C2)N2CCOCC2 |
| InChiKey | XSMSNFMDVXXHGJ-UHFFFAOYSA-N |
| InChi | InChI=1S/C23H21N7O/c1-2-17-14-25-28-20(17)13-16(1)21-15-30-8-7-24-23(30)22(27-21)26-18-3-5-19(6-4-18)29-9-11-31-12-10-29/h1-8,13-15H,9-12H2,(H,25,28)(H,26,27) |
| CAS Number | 1229208-44-9 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | 98% by HPLC |
| Storage | -20 ºC for 3 years |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
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