Firategrast
Catalog No: 16122946
CAS Number: 402567-16-2
Purity: 98%
Firategrast, also known as SB-683699 or T-0047, is an orally bioavailable alpha4 beta1/alpha4 beta7 integrin antagonist designed to reduce trafficking of lymphocytes into the central nervous system (CNS). This could decrease multiple sclerosis (MS) activity, but may compromise CNS immune surveillance. The integrins are a sort of transmembrane receptors that modulate the signal transduction from ECM to the cell. They are associated with a lot of diseases such as cancer, inflammation and thrombotic diseases.
For research use only. We do not sell to patients.
Chemical Information
| Name | Firategrast |
|---|---|
| Iupac Chemical Name | Firategrast |
| Synonyms | SB-683699; SB 683699; SB683699; T-0047; T 0047; T0047 |
| Molecular Formula | C27H27F2NO6 |
| Molecular Weight | 499.5108 |
| Smile | CCOCc1cc(c(c(c1)OC)c2ccc(cc2)C[C@@H](C(=O)O)NC(=O)c3c(cccc3F)F)OC |
| InChiKey | YLFZHHDVRSYTKT-NRFANRHFSA-N |
| InChi | InChI=1S/C27H27F2NO6/c1-4-36-15-17-13-22(34-2)24(23(14-17)35-3)18-10-8-16(9-11-18)12-21(27(32)33)30-26(31)25-19(28)6-5-7-20(25)29/h5-11,13-14,21H,4,12,15H2,1-3H3,(H,30,31)(H,32,33)/t21-/m0/s1 |
| CAS Number | 402567-16-2 |
| MDL | MFCD19443754 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | crystalline solid |
|---|---|
| Purity | 98% |
| Storage | 3 years -20ºCpowder |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
