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Fmk Catalog No : 188102

Chemical Information

Product NameFmk
Iupac Chemical Name1-[4-Amino-7-(3-hydroxypropyl)-5-(4-methylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]-2-fluoroethanone
Synonyms1-[4-Amino-7-(3-hydroxypropyl)-5-(4-methylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]-2-fluoroethanone;RSK2 kinase inhibitor;1-(4-Amino-7-(3-hydroxypropyl)-5-(p-tolyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl)-2-fluoroethanone
Molecular FormulaC18H19FN4O2
Molecular Weight342.37
SmileO=C(CF)C2=C(C3=CC=C(C)C=C3)C1=C(N)N=CN=C1N2CCCO
InChiKeyIKLGYJACVCXYIL-UHFFFAOYSA-N
InChi
Cas821794-92-7

Technical Data

AppearanceOff-white solid to white solid
Purity>98%
SolubilitySoluble in DMSO
StorageDry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Shipping ConditionShipped under ambient temperature
Quality control

Description

Potent irreversible RSK1/2 inhibitor (IC50 = 15 nM). Inactivates the C-terminal auto-kinase domain activity.

Chemical Structure

188102 - Fmk | CAS 821794-92-7

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