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GSK2269557 free base

Catalog No: 611826
CAS Number: 1254036-71-9
Purity: 98%

GSK-2269557 (free base) is a potent and selective PI3Kδ inhibitor over the closely related isoforms.

GSK-2269557 are active in a disease relevant brown Norway rat acute OVA model of Th2-driven lung inflammation. PI3Kδ is highly enriched

For research use only. We do not sell to patients.

Chemical Information

NameGSK2269557 free base
Iupac Chemical Name6-(1H-indol-4-yl)-4-(5-((4-isopropylpiperazin-1-yl)methyl)oxazol-2-yl)-1H-indazole
SynonymsGSK 2269557 free base; GSK-2269557 free base
Molecular FormulaC26H28N6O
Molecular Weight440.54
SmileN1C=CC2=C(C=CC=C12)C1=CC(=C2C=NNC2=C1)C=1OC(=CN1)CN1CCN(CC1)C(C)C
InChiKeyMCIDWGZGWVSZMK-UHFFFAOYSA-N
InChiInChI=1S/C26H28N6O/c1-17(2)32-10-8-31(9-11-32)16-19-14-28-26(33-19)22-12-18(13-25-23(22)15-29-30-25)20-4-3-5-24-21(20)6-7-27-24/h3-7,12-15,17,27H,8-11,16H2,1-2H3,(H,29,30)
CAS Number1254036-71-9
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Ordering Information

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Formulationcrystalline solid
Purity98%
Storage3 years -20℃powder
SolubilitySoluble in DMSO
Handling
Shipping ConditionShipped under ambient temperature as non-hazardous chemical.
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

611826 - GSK2269557 free base | CAS 1254036-71-9

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