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GSK2801

Catalog No: 16123012
CAS Number: 1619994-68-1
Purity: 98% 

GSK2801 is a A Selective Chemical Probe for BAZ2B/A bromodomains. BAZ2A/B belong to a family of ubiquitously expressed bromodomain containing proteins. Proteins of the BAZ family are characterized by a carboxy-terminal bromodomain adjacent to a PHD finger and a WACZ motif. In addition four other conserved motifs are typically found in the N-terminus of BAZ family members, namely the LH motif (a leucine-rich helical domain), the ZB2 motif and the BAZ 1 and BAZ 2 motifs. Little is known about the biological function of BAZ2B but it has been suggested to regulate nucleosome mobilization by the ATP-dependent chromatin remodeling factor ISWI. (http://www.thesgc.org/chemical-probes/GSK2801). 

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Chemical Information

NameGSK2801
Iupac Chemical NameGSK2801 
SynonymsGSK-2801; GSK 2801 
Molecular FormulaC20H21NO4S 
Molecular Weight371.45004 
SmileCS(=O)(=O)C1=C(C=CC=C1)C1=C2C=C(C=CN2C(=C1)C(C)=O)OCCC
InChiKeyKHWCPNJRJCNVRI-UHFFFAOYSA-N
InChiInChI=1S/C20H21NO4S/c1-4-11-25-15-9-10-21-18(14(2)22)13-17(19(21)12-15)16-7-5-6-8-20(16)26(3,23)24/h5-10,12-13H,4,11H2,1-3H3
CAS Number1619994-68-1
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Ordering Information

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Formulationcrystalline solid 
Purity98% 
Storage3 years -20ºCpowder 
SolubilitySoluble in DMSO 
Handling
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

16123012 - GSK2801 | CAS 1619994-68-1

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