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Gandotinib(LY2784544)

Catalog No: 91415
CAS Number: 1229236-86-5
Purity: 98% by HPLC

Gandotinib is an orally bioavailable imidazopyridazine and inhibitor of Janus kinase 2 mutant V617F (JAK2V617F)

For research use only. We do not sell to patients.

Chemical Information

NameGandotinib(LY2784544)
Iupac Chemical Name3-(4-chloro-2-fluorobenzyl)-2-methyl-N-(3-methyl-1H-pyrazol-5-yl)-8-(morpholinomethyl)imidazo[1,2-b]pyridazin-6-amine
SynonymsLY2784544;LY 2784544;LY-2784544;Gandotinib.
Molecular FormulaC23H25ClFN7O
Molecular Weight469.94
SmileClC1=CC(=C(CC2=C(N=C3N2N=C(C=C3CN3CCOCC3)NC3=CC(=NN3)C)C)C=C1)F
InChiKeySQSZANZGUXWJEA-UHFFFAOYSA-N
InChiInChI=1S/C23H25ClFN7O/c1-14-9-21(29-28-14)27-22-11-17(13-31-5-7-33-8-6-31)23-26-15(2)20(32(23)30-22)10-16-3-4-18(24)12-19(16)25/h3-4,9,11-12H,5-8,10,13H2,1-2H3,(H2,27,28,29,30)
CAS Number1229236-86-5
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Ordering Information

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Formulationcrystalline solid
Purity98% by HPLC
Storage3 years -20℃powder 6 months-80℃in solvent
SolubilitySoluble in DMSO to 20 mM
Handling
Shipping ConditionShipped under ambient temperature
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

91415 - Gandotinib(LY2784544) | CAS 1229236-86-5

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