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IMR-1A

Catalog No: 6111507
CAS Number: 331862-41-0
Purity: 98% 

IMR-1A is the metabolite of IMR-1. IMR-1 is a novel class of Notch inhibitors targeting the transcriptional activation with IC50 of 6 mol/L.

IMR-1 prevents the recruitment of Maml1 to the NTC on chromatin, inhibits Notch target gene transcription, and dramatically inhibits tumor growth .
A decrease in colony formation of Notch-dependent cell lines is observed upon treatment with IMR-1 when compared with the control (DMSO).

 

For research use only. We do not sell to patients.

Chemical Information

NameIMR-1A
Iupac Chemical NameIMR-1A 
SynonymsIMR1A; IMR 1A 
Molecular FormulaC13H11NO5S2 
Molecular Weight325.36 
InChiKey
InChi
CAS Number331862-41-0
Related CAS

Ordering Information

PackagingPriceAvailabilityPurityShipping Time
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Formulationcrystalline solid 
Purity98% 
Storage3 years -20ºCpowder 
SolubilitySoluble in DMSO 
Handling
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

6111507 - IMR-1A | CAS 331862-41-0

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