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INCB057643

Catalog No: 185232
CAS Number: 1820889-23-3
Purity: >98%

INCB057643 is a BET inhibitor. INCB054329 reduces homologous recombination efficiency and augments PARP inhibitor activity in ovarian cancer.

For research use only. We do not sell to patients.

Chemical Information

NameINCB057643
Iupac Chemical Name2,2,4-trimethyl-8-(6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-4-yl)-6-(methylsulfonyl)-2H-benzo[b][1,4]oxazin-3(4H)-one
SynonymsINCB057643; INCB-057643; INCB 057643;
Molecular FormulaC20H21N3O5S
Molecular Weight415.464
SmileCN(C(C(C)(C)O1)=O)C2=C1C(C(C3=C4NC=C3)=CN(C)C4=O)=CC(S(C)(=O)=O)=C2
InChiKeyVZSAMEOETVNDQH-UHFFFAOYSA-N
InChiInChI=1S/C20H21N3O5S/c1-20(2)19(25)23(4)15-9-11(29(5,26)27)8-13(17(15)28-20)14-10-22(3)18(24)16-12(14)6-7-21-16/h6-10,21H,1-5H3
CAS Number1820889-23-3
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Ordering Information

PackagingPriceAvailabilityPurityShipping Time
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FormulationOff-white solid to white solid
Purity>98%
StorageDry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
SolubilitySoluble in DMSO
Handling
Shipping ConditionShipped under ambient temperature
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

185232 - INCB057643 | CAS 1820889-23-3

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