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Eganelisib ( IPI-549 )

Catalog No: 711401
CAS Number: 1693758-51-8
Purity: ≧98.0%

Eganelisib (IPI-549) is a first-in-class, orally administered, highly selective PI3Kγ inhibitor with antitumor activity alone and in combination with programmed cell death protein 1/ligand 1 (PD-1/PD-L1) inhibitors in preclinical studies.

For research use only. We do not sell to patients.

Chemical Information

NameEganelisib ( IPI-549 )
Iupac Chemical Name(S)-2-amino-N-(1-(8-((1-methyl-1H-pyrazol-4-yl)ethynyl)-1-oxo-2-phenyl-1,2-dihydroisoquinolin-3-yl)ethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide 
SynonymsIPI-549 ; IPI 549 ; IPI549 ; Eganelisib
Molecular FormulaC30H24N8O2 
Molecular Weight528.576 
SmileO=C(C1=C2N=CC=CN2N=C1N)N[C@H](C3=CC4=C(C(N3C5=CC=CC=C5)=O)C(C#CC6=CN(C)N=C6)=CC=C4)C
InChiKeyXUMALORDVCFWKV-IBGZPJMESA-N
InChiInChI=1S/C30H24N8O2/c1-19(34-29(39)26-27(31)35-37-15-7-14-32-28(26)37)24-16-22-9-6-8-21(13-12-20-17-33-36(2)18-20)25(22)30(40)38(24)23-10-4-3-5-11-23/h3-11,14-19H,1-2H3,(H2,31,35)(H,34,39)/t19-/m0/s1
CAS Number1693758-51-8
Related CAS1693758-51-8

Ordering Information

PackagingPriceAvailabilityPurityShipping Time
BulkEnquiryEnquiryEnquiry
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FormulationLight-yellow solid 
Purity≧98.0%
StorageDry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years).
SolubilitySoluble in DMSO 
HandlingRefer to MSDS
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
HS Code2934200090
Coming soon.
TargetsPI3Kγ Inhibitor
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

711401 - Eganelisib ( IPI-549 ) | CAS 1693758-51-8

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