Login +0086-27-59253327 sales@sun-shinechem.com

KGP-94 Catalog No : 3291806

Chemical Information

Product NameKGP-94
Iupac Chemical Name2-((3-bromophenyl)(3-hydroxyphenyl)methylene)hydrazinecarbothioamide
SynonymsKGP-94;KGP94;KGP 94
Molecular FormulaC14H12BrN3OS
Molecular Weight350.23
SmileOC1=CC(/C(C2=CC=CC(Br)=C2)=N\NC(N)=S)=CC=C1
InChiKeyZDBKSZKTCPOBFR-LGMDPLHJSA-N
InChiInChI=1S/C14H12BrN3OS/c15-11-5-1-3-9(7-11)13(17-18-14(16)20)10-4-2-6-12(19)8-10/h1-8,19H,(H3,16,18,20)/b17-13-
Cas1131456-28-4

Technical Data

Appearanceoff-white solid
Purity>98%
SolubilitySoluble in DMSO, acetone, not in water
StorageDry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Shipping ConditionShipped under ambient temperature
Quality control HNMR

Description

KGP94 is a reversible, time-dependent and competitive inhibitor of human cathepsin L. ► KGP94 inhibits the activity of cathepsin L toward human type I collagen. ► KGP94 significantly impedes both migration and invasion of MDA-MB-231 human breast cancer cells. ► Molecular modeling places the thiocarbonyl of KGP94 in proximity to the active site Cys25. ► Significant growth retardation of C3H mouse mammary carcinomas is achieved with KGP94 treatment.

Chemical Structure

3291806 - KGP-94 | CAS 1131456-28-4

Package

SizePrice
Login to get price

Quick Order

Change

Contact Us