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KS176

Catalog No: 6111510
CAS Number: 1253452-78-6
Purity: 98% 

KS176 is a potent and selective inhibitor of the breast cancer resistance protein (BCRP) multidrug transporter (IC50 values are 0.59 and 1.39 M in Pheo A and Hoechst 33342 assays respectively). Displays no inhibitory activity against P-gp or MRP1.


 

For research use only. We do not sell to patients.

Chemical Information

NameKS176
Iupac Chemical NameN-[4-(2-Hydroxyethyl)phenyl]-2-[(4-nitrobenzoyl)amino]benzamide 
SynonymsKS 176; KS-176 
Molecular FormulaC22H19N3O5 
Molecular Weight405.4 
SmileOCCC1=CC=C(C=C1)NC(C1=C(C=CC=C1)NC(C1=CC=C(C=C1)[N+](=O)[O-])=O)=O
InChiKeyLTWQQWSXYYXVGA-UHFFFAOYSA-N
InChiInChI=1S/C22H19N3O5/c26-14-13-15-5-9-17(10-6-15)23-22(28)19-3-1-2-4-20(19)24-21(27)16-7-11-18(12-8-16)25(29)30/h1-12,26H,13-14H2,(H,23,28)(H,24,27)
CAS Number1253452-78-6
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Ordering Information

PackagingPriceAvailabilityPurityShipping Time
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Formulationcrystalline solid 
Purity98% 
Storage3 years -20ºCpowder 
SolubilitySoluble in DMSO 
Handling
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

6111510 - KS176 | CAS 1253452-78-6

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