LDN193189 Hydrochloride
Catalog No: 122830
CAS Number: 1062368-62-0
Purity: 98%
LDN193189 Hydrochloride is a selective BMP signaling inhibitor, inhibits the transcriptional activity of the BMP type I receptors ALK2 and ALK3 with IC50 of 5 nM and 30 nM, respectively, exhibits 200-fold selectivity for BMP versus TGF-β.
For research use only. We do not sell to patients.
Chemical Information
| Name | LDN193189 Hydrochloride |
|---|---|
| Iupac Chemical Name | 4-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline;hydrochloride |
| Synonyms | LDN 193189 hydrochloride; LDN-193189 hydrochloride |
| Molecular Formula | C25H23ClN6 |
| Molecular Weight | 442.943 |
| Smile | c1ccc2c(c1)c(ccn2)c3cnn4c3ncc(c4)c5ccc(cc5)N6CCNCC6.Cl |
| InChiKey | PCCDKTWDGDFRME-UHFFFAOYSA-N |
| InChi | InChI=1S/C25H22N6.ClH/c1-2-4-24-22(3-1)21(9-10-27-24)23-16-29-31-17-19(15-28-25(23)31)18-5-7-20(8-6-18)30-13-11-26-12-14-30;/h1-10,15-17,26H,11-14H2;1H |
| CAS Number | 1062368-62-0 |
| MDL | MFCD17392570 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | 98% |
| Storage | -20 ℃ for 3 years |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
