Lys05 trihydrochloride
Catalog No: 17030102
CAS Number: 1391426-24-6
Purity: 98%
Lys05, or Lys01 trihydrochloride, is a potent, water soluble lysosomal autophagy inhibitor. Lys05 is a previously undescribed dimeric chloroquine which more potently accumulates in the lysosome and blocks autophagy compared with HCQ. Lys05 produced more potent antitumor activity as a single agent both in vitro and in vivo in multiple human cancer cell lines and xenograft models compared with HCQ. Lys05 is therefore a new lysosomal autophagy inhibitor that has potential to be developed further into a drug for cancer and other medical applications.
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Chemical Information
| Name | Lys05 trihydrochloride |
|---|---|
| Iupac Chemical Name | Lys05 trihydrochloride |
| Synonyms | LYS-05 HCl; LYS05; LYS-05; Lys01 (trihydrochloride); Lys01 HCl salt |
| Molecular Formula | C23H26Cl5N5 |
| Molecular Weight | 549.75 |
| InChiKey | |
| InChi | |
| CAS Number | 1391426-24-6 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | off-white solid |
|---|---|
| Purity | 98% |
| Storage | 3 years -20ºCpowder |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. |
| HS Code |
Coming soon.
| Targets | |
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| Mechanism | |
| Cell study | |
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| Clinical study |
Not available
Chemical Structure
