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MELK-8a

Catalog No: L20331
CAS Number: 1922153-17-0
Purity: 98% Min.

MELK-8a Dihydrochloride is a novel inhibitor of maternal embryonic leucine zipper kinase (MELK) with an IC50 of 2 nM.

For research use only. We do not sell to patients.

Chemical Information

NameMELK-8a
Iupac Chemical NamePiperazine, 1-methyl-4-[4-[4-[3-(4-piperidinylmethoxy)-4-pyridinyl]-1H-pyrazol-1-yl]phenyl]-
SynonymsMELK-8a;Piperazine, 1-methyl-4-[4-[4-[3-(4-piperidinylmethoxy)-4-pyridinyl]-1H-pyrazol-1-yl]phenyl]-
Molecular FormulaC25H32N6O
Molecular Weight432.56
SmileCN1CCN(C2=CC=C(N3N=CC(C4=C(OCC5CCNCC5)C=NC=C4)=C3)C=C2)CC1
InChiKeyBLFBSGVUERKSST-UHFFFAOYSA-N
InChiInChI=1S/C25H32N6O/c1-29-12-14-30(15-13-29)22-2-4-23(5-3-22)31-18-21(16-28-31)24-8-11-27-17-25(24)32-19-20-6-9-26-10-7-20/h2-5,8,11,16-18,20,26H,6-7,9-10,12-15,19H2,1H3
CAS Number1922153-17-0
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Ordering Information

PackagingPriceAvailabilityPurityShipping Time
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FormulationSolid powder
Purity98% Min.
StorageDry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
SolubilitySoluble in DMSO
Handling
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

L20331 - MELK-8a | CAS 1922153-17-0

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