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MK-0812 Catalog No : 2017080111

Chemical Information

Product NameMK-0812
Iupac Chemical Name((1S,3R)-1-isopropyl-3-(((3S,4S)-3-methoxytetrahydro-2H-pyran-4-yl)amino)cyclopentyl)(3-(trifluoromethyl)-7,8-dihydro-1,6-naphthyridin-6(5H)-yl)methanone 
SynonymsMK-0812|MK 0812|MK0812. 
Molecular FormulaC24H34F3N3O3 
Molecular Weight469.5492 
SmileC(C)(C)[C@]1(C[C@@H](CC1)N[C@@H]1[C@@H](COCC1)OC)C(=O)N1CC=2C=C(C=NC2CC1)C(F)(F)F
InChiKeyMTMDXAIUENDNDL-RJSMDTJLSA-N
InChiInChI=1S/C24H34F3N3O3/c1-15(2)23(7-4-18(11-23)29-20-6-9-33-14-21(20)32-3)22(31)30-8-5-19-16(13-30)10-17(12-28-19)24(25,26)27/h10,12,15,18,20-21,29H,4-9,11,13-14H2,1-3H3/t18-,20+,21-,23+/m1/s1
Cas624733-88-6

Technical Data

Appearanceoff-white solid 
Purity98.0% 
SolubilitySoluble in DMSO 
Storage-20 ºC for 3 years 
Shipping ConditionShipped under ambient temperature 
Quality control

Description

MK-0812 is a potent and selective CCR2 antagonist. Chemokine (C-C motif) receptor 2 (CCR2) is central for the migration of monocytes into inflamed tissues. 

Chemical Structure

2017080111 - MK-0812 | CAS 624733-88-6

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