MK-0812
Catalog No: 2017080111
CAS Number: 624733-88-6
Purity: 98.0%
MK-0812 is a potent and selective CCR2 antagonist. Chemokine (C-C motif) receptor 2 (CCR2) is central for the migration of monocytes into inflamed tissues.
For research use only. We do not sell to patients.
Chemical Information
| Name | MK-0812 |
|---|---|
| Iupac Chemical Name | ((1S,3R)-1-isopropyl-3-(((3S,4S)-3-methoxytetrahydro-2H-pyran-4-yl)amino)cyclopentyl)(3-(trifluoromethyl)-7,8-dihydro-1,6-naphthyridin-6(5H)-yl)methanone |
| Synonyms | MK-0812|MK 0812|MK0812. |
| Molecular Formula | C24H34F3N3O3 |
| Molecular Weight | 469.5492 |
| Smile | C(C)(C)[C@]1(C[C@@H](CC1)N[C@@H]1[C@@H](COCC1)OC)C(=O)N1CC=2C=C(C=NC2CC1)C(F)(F)F |
| InChiKey | MTMDXAIUENDNDL-RJSMDTJLSA-N |
| InChi | InChI=1S/C24H34F3N3O3/c1-15(2)23(7-4-18(11-23)29-20-6-9-33-14-21(20)32-3)22(31)30-8-5-19-16(13-30)10-17(12-28-19)24(25,26)27/h10,12,15,18,20-21,29H,4-9,11,13-14H2,1-3H3/t18-,20+,21-,23+/m1/s1 |
| CAS Number | 624733-88-6 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | off-white solid |
|---|---|
| Purity | 98.0% |
| Storage | -20 ºC for 3 years |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
