NMS-P118
Catalog No: 17101311
CAS Number: 1262417-51-5
Purity: >98%
NMS-P118 is a potent, orally available, and highly selective PARP-1 inhibitor with excellent ADME and pharmacokinetic profiles and high efficacy in vivo both as a single agent and in combination with Temozolomide in MDA-MB-436 and Capan-1 xenograft models, respectively.
For research use only. We do not sell to patients.
Chemical Information
| Name | NMS-P118 |
|---|---|
| Synonyms | NMS-P118; NMS-P 118; NMS P118 |
| Molecular Formula | C20H24F3N3O2 |
| Molecular Weight | 395.43 |
| Smile | O=C(C1=CC(F)=CC(CN2C3CCN(C4CCC(F)(F)CC4)CC3)=C1C2=O)N |
| InChiKey | ARYVAQSYRLZVQD-UHFFFAOYSA-N |
| InChi | InChI=1S/C20H24F3N3O2/c21-13-9-12-11-26(19(28)17(12)16(10-13)18(24)27)15-3-7-25(8-4-15)14-1-5-20(22,23)6-2-14/h9-10,14-15H,1-8,11H2,(H2,24,27) |
| CAS Number | 1262417-51-5 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | o |
|---|---|
| Purity | >98% |
| Storage | 3 years -20ºCpowder |
| Solubility | Soluble in DMSO, not in water |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
