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Nolatrexed HCl Catalog No : 185166

Chemical Information

Product NameNolatrexed HCl
Iupac Chemical Name2-Amino-6-methyl-5-(4-pyridylthio)-1H-quinazolin-4-one dihydrochloride
SynonymsAG337; AG 337; AG-337; Nolatrexed HCl; Nolatrexed dihydrochloride; brand name: Thymitaq.
Molecular FormulaC14H14Cl2N4OS
Molecular Weight357.253
SmileO=C1N=C(N)NC2=C1C(SC3=CC=NC=C3)=C(C)C=C2.[H]Cl.[H]Cl
InChiKeyPJKVJJYMWOCLIJ-UHFFFAOYSA-N
InChiInChI=1S/C14H12N4OS.2ClH/c1-8-2-3-10-11(13(19)18-14(15)17-10)12(8)20-9-4-6-16-7-5-9;;/h2-7H,1H3,(H3,15,17,18,19);2*1H
Cas152946-68-4

Technical Data

AppearanceOff-white solid to white solid
Purity>98%
SolubilitySoluble in DMSO
StorageDry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Shipping ConditionShipped under ambient temperature
Quality control

Description

Nolatrexed, also known as AG337, is a thymidylate synthase inhibitor with potential anticancer activity.

Chemical Structure

185166 - Nolatrexed HCl | CAS 152946-68-4

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