Omapatrilat
Catalog No: 17030903
CAS Number: 167305-00-2
Purity: 98%
Omapatrilat is a novel antihypertensive agent that inhibits both neutral endopeptidase (NEP) and angiotensin converting enzyme. NEP inhibition results in elevated natriuretic peptide levels, promoting natriuresis, diuresis, vasodilation, and reductions in preload and ventricular remodeling. The drug was promoted for possible uses in congestive heart failure.
For research use only. We do not sell to patients.
Chemical Information
| Name | Omapatrilat |
|---|---|
| Iupac Chemical Name | (4S,7S,10aS)-4-((S)-2-mercapto-3-phenylpropanamido)-5-oxooctahydro-2H-pyrido[2,1-b][1,3]thiazepine-7-carboxylic acid |
| Synonyms | BMS 186716; BMS-186716; BMS186716; Vanlev; Omapatrilat |
| Molecular Formula | C19H24N2O4S2 |
| Molecular Weight | 408.5349 |
| Smile | S[C@H](C(=O)N[C@@H]1C(N2[C@@H](SCC1)CCC[C@H]2C(=O)O)=O)CC2=CC=CC=C2 |
| InChiKey | LVRLSYPNFFBYCZ-VGWMRTNUSA-N |
| InChi | InChI=1S/C19H24N2O4S2/c22-17(15(26)11-12-5-2-1-3-6-12)20-13-9-10-27-16-8-4-7-14(19(24)25)21(16)18(13)23/h1-3,5-6,13-16,26H,4,7-11H2,(H,20,22)(H,24,25)/t13-,14-,15-,16-/m0/s1 |
| CAS Number | 167305-00-2 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | off-white solid |
|---|---|
| Purity | 98% |
| Storage | 3 years -20ºCpowder |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
