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Omecamtiv mecarbil (CK-1827452)

Catalog No: 100901
CAS Number: 873697-71-3
Purity: 98% 

Omecamtiv mecarbil is a novel, small-molecule, direct activator of cardiac myosin, the motor protein that causes cardiac contraction. It is being evaluated as a potential treatment of heart failure in both intravenous and oral formulations with application across the continuum of care for heart failure patients from in-hospital to outpatient settings. 

For research use only. We do not sell to patients.

Chemical Information

NameOmecamtiv mecarbil (CK-1827452)
Iupac Chemical Namemethyl 4-(2-fluoro-3-(3-(6-methylpyridin-3-yl)ureido)benzyl)piperazine-1-carboxylate 
SynonymsCK 1827452; CK1827452 
Molecular FormulaC20H24FN5O3 
Molecular Weight401.43 
SmileO=C(N1CCN(CC2=CC=CC(NC(NC3=CC=C(C)N=C3)=O)=C2F)CC1)OC
InChiKeyRFUBTTPMWSKEIW-UHFFFAOYSA-N
InChiInChI=1S/C20H24FN5O3/c1-14-6-7-16(12-22-14)23-19(27)24-17-5-3-4-15(18(17)21)13-25-8-10-26(11-9-25)20(28)29-2/h3-7,12H,8-11,13H2,1-2H3,(H2,23,24,27)
CAS Number873697-71-3
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Ordering Information

PackagingPriceAvailabilityPurityShipping Time
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FormulationSolid powder 
Purity98% 
Storage-20 ºC for 3 years 
SolubilitySoluble in DMSO, Ethanol, and Water 
Handling
Shipping ConditionShipped under ambient temperature 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

100901 - Omecamtiv mecarbil (CK-1827452) | CAS 873697-71-3

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