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PF-06747775

Catalog No: 175161
CAS Number: 1776112-90-3
Purity: 98% by HNMR/HPLC 

PF-06747775(PF06747775;CAS 1776112-90-3) is an orally available inhibitor of the epidermal growth factor receptor (EGFR) mutant form T790M, with potential antineoplastic activity.

For research use only. We do not sell to patients.

Chemical Information

NamePF-06747775
Iupac Chemical NameN-((3R,4R)-4-fluoro-1-(6-((3-methoxy-1-methyl-1H-pyrazol-4-yl)amino)-9-methyl-9H-purin-2-yl)pyrrolidin-3-yl)acrylamide 
SynonymsPF-06747775;PF06747775;PF 06747775 
Molecular FormulaC18H22FN9O2 
Molecular Weight415.4 
SmileC=CC(N[C@@H]1CN(C2=NC(NC3=CN(C)N=C3OC)=C4N=CN(C)C4=N2)C[C@H]1F)=O
InChiKeyJYIUNVOCEFIUIU-GHMZBOCLSA-N
InChiInChI=1S/C18H22FN9O2/c1-5-13(29)21-11-8-28(6-10(11)19)18-23-15(14-16(24-18)26(2)9-20-14)22-12-7-27(3)25-17(12)30-4/h5,7,9-11H,1,6,8H2,2-4H3,(H,21,29)(H,22,23,24)/t10-,11-/m1/s1
CAS Number1776112-90-3
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Ordering Information

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Formulationcrystalline solid 
Purity98% by HNMR/HPLC 
Storage3 years -20ºCpowder;6 months-80ºCin solvent 
SolubilitySoluble in DMSO, not in water 
Handling
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

175161 - PF-06747775 | CAS 1776112-90-3

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