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R-GNE-140

Catalog No: 18432
CAS Number: 2003234-63-5
Purity: >98%

R-GNE-140 a novel potent lactate dehydrogenase (LDHA) inhibitor with IC50 3nM for LDHA and 5 nM for LDHB.

For research use only. We do not sell to patients.

Chemical Information

NameR-GNE-140
Iupac Chemical Name(R)-3-((2-Chlorophenyl)thio)-4-hydroxy-6-(4-morpholinophenyl)-6-(thiophen-3-yl)-5,6-dihydropyridin-2(1H)-one
SynonymsR-GNE-140; (R)-GNE-140; GNE 140; GNE140.
Molecular FormulaC25H23ClN2O3S2
Molecular Weight499.04
SmileO=C1C(SC2=CC=CC=C2Cl)=C(O)C[C@](C3=CSC=C3)(C4=CC=C(N5CCOCC5)C=C4)N1
InChiKeySUFXXEIVBZJOAP-RUZDIDTESA-N
InChiInChI=1S/C25H23ClN2O3S2/c26-20-3-1-2-4-22(20)33-23-21(29)15-25(27-24(23)30,18-9-14-32-16-18)17-5-7-19(8-6-17)28-10-12-31-13-11-28/h1-9,14,16,29H,10-13,15H2,(H,27,30)/t25-/m1/s1
CAS Number2003234-63-5
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Ordering Information

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FormulationOff-white solid to white solid
Purity>98%
StorageDry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
SolubilitySoluble in DMSO, not in water
Handling
Shipping ConditionShipped under ambient temperature
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

18432 - R-GNE-140 | CAS 2003234-63-5

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