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SU5402 Catalog No : 174191

Chemical Information

Product NameSU5402
Iupac Chemical Name(Z)-3-(4-methyl-2-((2-oxoindolin-3-ylidene)methyl)-1H-pyrrol-3-yl)propanoic acid 
SynonymsSU5402;SU-5402;SU 5402 
Molecular FormulaC17H16N2O3 
Molecular Weight296.3 
SmileO=C(O)CCC1=C(/C=C2C(NC3=C\2C=CC=C3)=O)NC=C1C
InChiKeyJNDVEAXZWJIOKB-JYRVWZFOSA-N
InChiInChI=1S/C17H16N2O3/c1-10-9-18-15(11(10)6-7-16(20)21)8-13-12-4-2-3-5-14(12)19-17(13)22/h2-5,8-9,18H,6-7H2,1H3,(H,19,22)(H,20,21)/b13-8-
Cas215543-92-3

Technical Data

Appearanceyellow powder 
Purity98% by HNMR/HPLC
SolubilitySoluble in DMSO, not in water 
Storage3 years -20ºCpowder 6 months-80ºCin solvent 
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. 
Quality control

Description

SU5402 is a fibroblast growth factor receptor (FGFR)-specific tyrosine kinase inhibitor. Multiple myeloma studies suggest that SU 5402 inhibits FGFR3 phosphorylation in vitro. SU5402 is also very potent in inhibiting VEGFR, and PDGFR.  Research shows that it inhibits embryonic left-right determination and exhibits potent anticancer activity in vitro and in vivo. 

Chemical Structure

174191 - SU5402 | CAS 215543-92-3

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