Selumetinib
Catalog No: 52571
CAS Number: 606143-52-6
Purity: 98%
Selumetinib (AZD6244; ARRY-142886) is a potent, highly selective MEK1 inhibitor with IC50 of 14 nM, also inhibits ERK1/2 phosphorylation with IC50 of 10 nM, no inhibition to p38, MKK6, EGFR, ErbB2, ERK2, B-Raf, etc.
For research use only. We do not sell to patients.
Chemical Information
| Name | Selumetinib |
|---|---|
| Molecular Formula | C17H15BrClFN4O3 |
| Molecular Weight | 457.68 |
| Smile | Cn1cnc2c1cc(c(c2F)Nc3ccc(cc3Cl)Br)C(=O)NOCCO |
| InChiKey | CYOHGALHFOKKQC-UHFFFAOYSA-N |
| InChi | InChI=1S/C17H15BrClFN4O3/c1-24-8-21-16-13(24)7-10(17(26)23-27-5-4-25)15(14(16)20)22-12-3-2-9(18)6-11(12)19/h2-3,6-8,22,25H,4-5H2,1H3,(H,23,26) |
| CAS Number | 606143-52-6 |
| MDL | MFCD11977472 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Purity | 98% |
|---|---|
| Handling | |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
