+0086-27-59253327 sales@sun-shinechem.com

Trametinib (GSK1120212) Catalog No : 52109

Chemical Information

Product NameTrametinib (GSK1120212)
Iupac Chemical NameN-(3-(3-cyclopropyl-5-(2-fluoro-4-iodophenylamino)-6,8-dimethyl-2,4,7-trioxo-3,4,6,7-tetrahydropyrido[4,3-d]pyrimidin-1(2H)-yl)phenyl)acetamide 
SynonymsTrametinib,GSK1120212 
Molecular FormulaC26H23FIN5O4 
Molecular Weight615.39 
SmileC1(CC1)N1C(N(C=2C(C1=O)=C(N(C(C2C)=O)C)NC2=C(C=C(C=C2)I)F)C=2C=C(C=CC2)NC(C)=O)=O
InChiKeyLIRYPHYGHXZJBZ-UHFFFAOYSA-N
InChiInChI=1S/C26H23FIN5O4/c1-13-22-21(23(31(3)24(13)35)30-20-10-7-15(28)11-19(20)27)25(36)33(17-8-9-17)26(37)32(22)18-6-4-5-16(12-18)29-14(2)34/h4-7,10-12,17,30H,8-9H2,1-3H3,(H,29,34)
Cas871700-17-3

Technical Data

Appearanceoff-white solid 
Purity98% 
Solubility5mg/ml in DMSO 
Storage3 years -20ºCpowder 6 months-80ºCin solvent 
Shipping ConditionShipped under ambient temperature 
Quality control

Description

Trametinib (GSK1120212) is a highly specific and potent MEK1/2 inhibitor with IC50 of 0.92 nM/1.8 nM, no inhibition of the kinase activities of c-Raf, B-Raf, ERK1/2. 

Chemical Structure

52109 - Trametinib (GSK1120212) | CAS 871700-17-3

Package

SizePrice

Quick Order

Change

Contact Us