VLX1570
Catalog No: 611932
CAS Number: 1431280-51-1
Purity: 98%
VLX1570 is a competitive inhibitor of proteasome DUB activity with IC50 ranging from 4.2 uM to 8.6 uM.
VLX1570 inhibits proteasome deubiqu-itinase activity and induces accumulation of high molecularweight polyubiquitinated proteins in cells.
Knock-down of USP14 in multiple myeloma cells induces loss of cell viability
VLX1570 induces accumulation of polyubiquitin chains and elicits apoptosis of multiple myeloma cells
VLX1570 induces apoptosis and cell death of MM cells
For research use only. We do not sell to patients.
Chemical Information
| Name | VLX1570 |
|---|---|
| Iupac Chemical Name | VLX1570 |
| Synonyms | VLX 1570; VLX-1570 |
| Molecular Formula | C23H17F2N3O6 |
| Molecular Weight | 469.39 |
| InChiKey | |
| InChi | |
| CAS Number | 1431280-51-1 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | crystalline solid |
|---|---|
| Purity | 98% |
| Storage | 3 years -20ºCpowder |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
