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Cobicistat(GS-9350)

编号: 51906
Cas号: 1004316-88-4
纯度: 98% 

Cobicistat is a potent inhibitor of cytochrome P450 3A enzymes, including the important CYP3A4 subtype. It also inhibits intestinal transport proteins, increasing the overall absorption of several HIV medications, including atazanavir, darunavir and tenofovir alafenamide fumarate.

仅供研究使用。 我们不向患者出售。

化学信息

名称Cobicistat(GS-9350)
Iupac 化学名称2,7,10,12-Tetraazatridecanoic acid, 12-methyl-13-[2-(1-methylethyl)-4-thiazolyl]-9-[2-(4-morpholinyl)ethyl]-8,11-dioxo-3,6-bis(phenylmethyl)-, 5-thiazolylmethyl ester, (3R,6R,9S)- 
同义词Cobicistat;GS-9350;Tybost(trade name);GS9350;GS 9350 
英文同义词Cobicistat;GS-9350;Tybost(trade name);GS9350;GS 9350 
分子式C40H53N7O5S2 
分子量776.02 
SmileO=C(OCC1=CN=CS1)N[C@@H](CC2=CC=CC=C2)CC[C@H](CC3=CC=CC=C3)NC([C@H](CCN4CCOCC4)NC(N(C)CC5=CSC(C(C)C)=N5)=O)=O
InChiKeyZCIGNRJZKPOIKD-CQXVEOKZSA-N
InChiInChI=1S/C40H53N7O5S2/c1-29(2)38-43-34(27-53-38)25-46(3)39(49)45-36(16-17-47-18-20-51-21-19-47)37(48)42-32(22-30-10-6-4-7-11-30)14-15-33(23-31-12-8-5-9-13-31)44-40(50)52-26-35-24-41-28-54-35/h4-13,24,27-29,32-33,36H,14-23,25-26H2,1-3H3,(H,42,48)(H,44,50)(H,45,49)/t32-,33-,36+/m1/s1
Cas号1004316-88-4
相关CAS号

订购信息

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外观性状off-white solid 
纯度98% 
存储3 years -20ºCpowder 
可溶性5mg/ml in DMSO 
处理方式
运输条件Shipped under ambient temperature. 
海关编码
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Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

化学结构

51906 - Cobicistat(GS-9350) | CAS 1004316-88-4

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