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IU1 编号 : 51637

化学信息

产品英文名称IU1
Iupac 化学名称1-[1-(4-Fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(1-pyrrolidinyl)ethanone 
同义词IU1 
英文同义词IU1 
分子式C18H21FN2O 
分子量300.37 
SmileCC1=CC(C(CN2CCCC2)=O)=C(C)N1C3=CC=C(F)C=C3
InChiKeyJUWDSDKJBMFLHE-UHFFFAOYSA-N
InChiInChI=1S/C18H21FN2O/c1-13-11-17(18(22)12-20-9-3-4-10-20)14(2)21(13)16-7-5-15(19)6-8-16/h5-8,11H,3-4,9-10,12H2,1-2H3
Cas314245-33-5

技术数据

外观light yellow solid 
纯度98% 
可溶性5mg/ml in DMSO 
存储3 years -20ºCpowder 
运输条件Shipped under ambient temperature. 
质量控制

产品详情

IU1 is a reversible and specific inhibitor of proteasome-associating Usp14. It does not inhibit other deubiquitinating enzymes of the 26S proteasome. It partially inhibits the ubiquitin chain trimming activity of the 26S proteasome, which could function to stimulate the degradation of some proteasomal substrates.

 

结构

51637 - IU1 | CAS 314245-33-5

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