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抑制剂/受体激动剂
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Epigenetics
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Angiogenesis
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Cytoskeletal Signaling
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Metabolism
Anti-infection
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others
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+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
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TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
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Membrane Transporter/Ion Channel
others
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Quinolines
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产品名字索引 B
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产品名字索引 B
Bomedemstat
(Catalog# : 24001, Cas# :
1990504-34-1
)
Bomedemstat 是一种口服的、不可逆的赖氨酸特异性去甲基酶 1 (LSD1)
Brexpiprazole
(Catalog# : 20620, Cas# :
913611-97-9
)
Brexpiprazole, also known as OPC-34712, is a novel D2 dopamine partial agonist called
Berotralstat HCl
(Catalog# : 20619, Cas# :
1809010-52-3
)
Berotralstat HCl is a novel selective inhibitor of plasma kallikrein, blocking the en
Belzutifan
(Catalog# : 20606, Cas# :
1672668-24-4
)
Belzutifan, also known as PT2977 and MK-6482, is HIF-2alpha inhibitor. PT2977 binds t
BI-1467335 HCl
(Catalog# : 20601, Cas# :
1478364-68-9
)
BI-1467335, also known as PXS-4728A, is a SSAO/VAP inhibitor potentially for the trea
Bozitinib
(Catalog# : 20599, Cas# :
1440964-89-5
)
Bozitinib is a highly selective c-MET kinase inhibitor with blood-brain barrier perme
BMS-986176
(Catalog# : 20597, Cas# :
1815613-42-3
)
BMS-986176, also known as LX9211, is a highly selective, CNS penetrant, potent AAK1 i
BBT
(Catalog# : 20570, Cas# :
445000-45-3
)
BBT is an enhancer of impaired glucose-stimulated insulin secretion (GSIS).
1,1'-Biphenyl, 2-iodo-
(Catalog# : 20564, Cas# :
2113-51-1
)
1,1'-Biphenyl, 2-iodo- is a biochemical.
BML-278
(Catalog# : 20554, Cas# :
120533-76-8
)
BML-278 is an activator of sirtuin 1 (SIRT1) that has an EC150 value (effective conce
BSJ-04-122
(Catalog# : 20550, Cas# :
2513289-74-0
)
brigimadlin
(Catalog# : 20533, Cas# :
2095116-40-6
)
Brigimadlin is an E3 ubiquitin-protein ligase Mdm2 inhibitor with potential as an ant
BMS-986120
(Catalog# : 20519, Cas# :
1478712-37-6
)
BMS-986120 is a potent and selective oral antagonist of protease-activated receptor-4
BMS-986141
(Catalog# : 20518, Cas# :
1478711-48-6
)
BMS-986141 is an Orally-Active Small-Molecule Antagonist of the Platelet Protease-Act
BDTX-1535
(Catalog# : 20512, Cas# :
2607829-38-7
)
BDTX-1535 是一种突变选择性、不可逆的第四代 EGFR 抑制剂。
Brepocitinib Tosylate
(Catalog# : 232252, Cas# :
2140301-96-6
)
Brepocitinib ( PF-06700841 ) is an orally available, selective inhibitor of non-recep
BRD4 degrader AT1
(Catalog# : 20496, Cas# :
2098836-45-2
)
BRD4 degrader AT1 is an analogue of MZ1. It shows improved selectivity for BRD4 degra
BJJF078
(Catalog# : 20492, Cas# :
2531244-56-9
)
BJJF078 is a potent inhibitor of recombinant human and mouse Transglutaminase enzyme
BRD0639
(Catalog# : 20485, Cas# :
2760881-74-9
)
BRD0639 is a potent PRMT5 inhibitor. BRD0639 engages the target in cells, disrupts PR
BI 1015550 ( Nerandomilast )
(Catalog# : 230402, Cas# :
1423719-30-5
)
BI 1015550 ( Nerandomilast ) 是一种口服磷酸二酯酶 4B (PDE4B) 优先抑制剂
BT44
(Catalog# : 20469, Cas# :
924759-42-2
)
BT44 is a novel RET agonist for the treatment of experimental neuropathies.
Brepocitinib ( PF-06700841 )
(Catalog# : 232251, Cas# :
1883299-62-4
)
Brepocitinib 是一种潜在的 TYK2 和 JAK1双重选择性抑制剂,IC50 分别为
BIIB068
(Catalog# : 20453, Cas# :
1798787-27-5
)
Baxdrostat
(Catalog# : 20451, Cas# :
1428652-17-8
)
Baxdrostat is an aldosterone synthase inhibitor.
BMS-986251
(Catalog# : 20445, Cas# :
2114324-48-8
)
BMS-986195
(Catalog# : 20444, Cas# :
1912445 -55-6
)
Branebrutinib
(Catalog# : 20428, Cas# :
1912445-55-6
)
Branebrutinib, also known as BMS-986195, is a potent, covalent, irreversible inhibito
Bexotegrast ( PLN-74809 )
(Catalog# : 171680, Cas# :
2376257-44-0
)
Bexotegrast(同义词:PLN-74809)是一种小分子、双重选择性 αVβ1 / α
4-溴-2-氰基-6-甲氧基吡啶
(Catalog# : 171653, Cas# :
886372-53-8
)
4-溴-2-氰基-6-甲氧基吡啶, CAS 886372-53-8
1-(4-溴-6-甲基吡啶-2-基)乙-1-酮
(Catalog# : 171454, Cas# :
1060810-24-3
)
1-(4-溴-6-甲基吡啶-2-基)乙-1-酮, CAS 1060810-24-3.
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产品分类
信号通路
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
PLX8394
(Catalog# : 20613, Cas# :
1393466-87-9
)
PLX8394 is an orally bioavailable inhibitor of serine/threonine-protein kinase B-raf
Zelasudil
(Catalog# : 24014, Cas# :
2365193-22-0
)
Zelasudil 是一种有效的、高选择性的口服活性抑制剂,针对 Rho 相关
Ziftomenib ( KO-539 )
(Catalog# : 24013, Cas# :
2134675-36-6
)
Ziftomenib 是一种口服、有效、选择性的小分子抑制剂,针对 menin 和
Zunsemetinib
(Catalog# : 24012, Cas# :
1640282-42-3
)
Zunsemetinib是一种在研口服丝裂原活化蛋白激酶活化蛋白激酶2(MK2
Zongertinib ( BI 1810631 )
(Catalog# : 24011, Cas# :
2728667-27-2
)
Zongertinib [BI 1810631] 是一种人表皮生长因子受体 2 (HER2) 抑制剂。
Zasocitinib
(Catalog# : 24010, Cas# :
2272904-53-5
)
Zasocitinib是一种作用于非受体酪氨酸蛋白激酶 (TYK2)靶点的抑制
RNK-05047
(Catalog# : 24008, Cas# :
2503036-46-0
)
RNK-05047 为BRD4降解剂,其在小鼠荷瘤异种移植模型中展现出显著抑
Asengeprast (FT011)
(Catalog# : 24009, Cas# :
1001288-58-9
)
Asengeprast (FT011) 是一种抗纤维化剂,降低胶原蛋白 I 和 III 的 mRNA
ERAS-801 ( JGK-068S )
(Catalog# : 20635, Cas# :
2490431-16-6
)
ERAS-801 ( JGK-068S ) 是一种有效的 EGFR 抑制剂。
T-1095
(Catalog# : 24004, Cas# :
209746-59-8
)
T-1095 is a potent and selective inhibitor of Na+-glucose cotransporters (SGLTs).