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PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
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TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
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Immunology & Inflammation
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Cas Index 1
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Cas Index 1
1216665-49-4 | APY29
(Catalog# : 011108)
APY29 is an allosteric modulator of IRE1; inhibits IRE1 autophosphorylation (IC50 = 2
1228237-57-7 | ARQ-736
(Catalog# : 011104)
ARQ 736 is a potent and selective BRAF inhibitor.
1035270-39-3 | AZD4547
(Catalog# : 010820)
AZD4547 is a novel selective FGFR inhibitor targeting FGFR1/2/3 with IC50 of 0.2 nM/2
1236699-92-5 | AS703026
(Catalog# : 010808)
AS703026 is an orally bioavailable small-molecule inhibitor of MEK1 and MEK2 (MEK1/2)
1035227-43-0 | AZ505
(Catalog# : 010803)
AZ505 is a potent and highly selective inhibitor of the oncogenic protein SMYD2(IC50=
154323-57-6 | Almotriptan
(Catalog# : 010418)
Almotriptan is a 5-HT1B/1D-receptor agonist used to treat migraine.
164178-33-0 | AM630
(Catalog# : 010410)
AM630 is a selectivity CB2 antagonist with Ki of 31.2 nM; > 150 fold selectivity o
1009298-09-2 | AZD-8055
(Catalog# : 123019)
AZD-8055 is an inhibitor of the mammalian target of rapamycin (mTOR) with potential a
1627494-13-6 | AZD8186
(Catalog# : 122925)
AZD8186 is an isoform-specific small-molecule PI3K inhibitor, potently inhibits PI3K
1448346-63-1 | AG-120
(Catalog# : 122906)
AG-120 is an orally available inhibitor of isocitrate dehydrogenase type 1 (IDH1), wi
1034148-04-3 | AZD-5423
(Catalog# : 122902)
Coming soon!
183232-66-8 | AM251
(Catalog# : 122842)
AM251 is a potent CB1 receptor antagonist (IC50 = 8 nM, Ki = 7.49 nM) that displays 3
134523-01-6 | Atorvastatin sodium
(Catalog# : 122303)
Atorvastatin has the potential to ameliorate arsenic-induced vascular dysfunction and
110267-81-7 | Amrubicin
(Catalog# : 122211)
Amrubicin is a novel anthracycline derivative for treatment of bladder carcinoma.
134036-52-5 | AG 490
(Catalog# : 122210)
AG-490 is a tyrosine kinase inhibitor of JAK2, EGFR, and Neu that belongs to the fami
121268-17-5 | Alendronate sodium trihydrate
(Catalog# : 120409)
Coming soon!
1345847-93-9 | Altiratinib
(Catalog# : 120104)
Altiratinib is a novel c-MET/TIE-2/VEGFR inhibitor; effectively reduce tumor burden i
1355326-35-0 | AGI-5198
(Catalog# : 120103)
AGI-5198 is a novel R132H-IDH1 inhibitor, identified through a high-throughput screen
1166227-08-2 | A66
(Catalog# : 120101)
A66 is a potent and specific p110 inhibitor with IC50 of 32 nM, >100 fold selectiv
1352226-88-0 | AZD6738
(Catalog# : 110906)
AZD6738 is an orally available morpholino-pyrimidine-based inhibitor of ataxia telang
106447-97-6 | 2-Amino-4-(trifluoromethyl)pyridine
(Catalog# : 110214)
Coming soon!
141430-65-1 | ABT-751
(Catalog# : 102613)
ABT-751 is a novel bioavailable tubulin-binding and antimitotic sulfonamide agent wit
1613393-51-3 | (3aR,5S)-3a,4,5,7-tetrahydro-5-methyl-3H-pyrano[3,4-c]isoxazole
(Catalog# : 91823)
Coming soon!
1220327-45-6 | (3aR,5R)-3a,4,5,7-tetrahydro-5-methyl-3H-pyrano[3,4-c]isoxazole
(Catalog# : 91803)
Coming soon!
14166-28-0 | (3aR,4S,7R,7aS)-Hexahydro-4,7-methanoisobenzofuran-1,3-dione
(Catalog# : 91404)
The related APILurasidone hydrochlorideThe related intermediates4-(1,2-Benzothiazol-3
14805-29-9 | (3aR,4S,7R,7aS)-Hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione
(Catalog# : 91401)
The related APILurasidone hydrochlorideThe related intermediates4-(1,2-Benzothiazol-3
1626387-80-1 | AZD3759
(Catalog# : 901301)
AZD3759 isan orally available inhibitor of the epidermal growth factor receptor (EGFR
1664-54-6 | 3-(3-Aminophenyl)propanoic acid
(Catalog# : 90607)
Coming soon!
1035229-35-6 | 8-(2-aminoethyl)-5-hydroxy-4H-1,4-benzoxazin-3-one,hydrochloride
(Catalog# : 82801)
Coming soon!
173334-57-1 | Aliskiren
(Catalog# : 82708)
Aliskiren(CGP 60536) is a direct renin inhibitor with IC50 of 1.5 nM.
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
2365193-22-0 | Zelasudil
(Catalog# : 24014)
Zelasudil is a potent, highly selective and orally-active inhibitor that targets Rho-
2134675-36-6 | Ziftomenib ( KO-539 )
(Catalog# : 24013)
Ziftomenib is an oral, potent, and selective small molecule inhibitor that targets th
1640282-42-3 | Zunsemetinib
(Catalog# : 24012)
Zunsemetinib is an investigational oral mitogen-activated protein kinase-activated pr
2728667-27-2 | Zongertinib
(Catalog# : 24011)
Zongertinib [BI 1810631] is a human epidermal growth factor receptor 2 (HER2) inhibit
2272904-53-5 | Zasocitinib
(Catalog# : 24010)
Zasocitinib is under development for the treatment of moderate to severe plaque psori
2503036-46-0 | RNK-05047
(Catalog# : 24008)
RNK-05047 is a PROTAC degrader of BRD4 which displays significant tumor growth inhibi
1001288-58-9 | Asengeprast (FT011)
(Catalog# : 24009)
Asengeprast (FT011) is an anti-fibrotic agent thatreduces mRNA expression of collagen
2490431-16-6 | ERAS-801 ( JGK-068S )
(Catalog# : 20635)
ERAS-801 ( JGK-068S ) is a potent EGFR inhibitor.
209746-59-8 | T-1095
(Catalog# : 24004)
T-1095 is a potent and selective inhibitor of Na+-glucose cotransporters (SGLTs).
2739866-40-9 | NVL-655 ( ALK-IN-27 )
(Catalog# : 24003)
NVL-655 is a novel, brain-penetrant, ALK-selective inhibitor that was designed to add