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Epigenetics
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Angiogenesis
Apoptosis
Autophagy
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MAPK
Cytoskeletal Signaling
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+86-17702719238
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Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
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GPCR & G Protein
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Cas Index 2
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Cas Index 2
2387898-69-1 | ATH434 mesylate
(Catalog# : 20638)
ATH434, is an oral agent designed to inhibit the aggregation of pathological proteins
2394874-66-7 | Adrixetinib
(Catalog# : 20617)
Adrixetinib is a tyrosine kinase inhibitor with potential use as an antineoplastic ag
2285440-39-1 | Alpibectir
(Catalog# : 20616)
Alpibectir is an antibacterial agent.
2229711-68-4 | ARV-471
(Catalog# : 20609)
2025360-90-9 | Arazasetron
(Catalog# : 20535)
Arazasetron is an antiemetic which acts as a 5-HT3 receptor antagonist, pKi = 9.27.
2143061-81-6 | AZD5991
(Catalog# : 20508)
AZD5991 is a potent and selective Mcl-1 inhibitor for treatment of hematologic cancer
2750001-23-9 | AZD0095
(Catalog# : 237072)
AZD0095 is a Selective Inhibitor of Monocarboxylate Transporter 4 (MCT4) for Oncology.
2041075-86-7 | AZD5718
(Catalog# : 20476)
AZD5718 is a novel Inhibitor of 5-Lipoxygenase Activating Protein(FLAP) for Treatment
254751-08-1 | Acetic acid, 2-[[2-(1,1-diMethylethyl)phenyl]aMino]-2-oxo-
(Catalog# : 20415)
2492-30-0 | ACETOPHENONESEMICARBAZONE
(Catalog# : 20413)
256448-15-4 | 4-Aza-1-azoniabicyclo[2.2.2]octane, 1,1'-(1,12-dodecanediyl)bis-, dibromide (9CI)
(Catalog# : G20382)
2119669-71-3 | Asciminib HCl
(Catalog# : 1711223)
Asciminib, also known as ABL001, is a potent allosteric inhibitor of BCR-ABL.
2095719-92-7 | ASTX-029
(Catalog# : 20298)
ASTX029 is a highly potent and selective dual-mechanism ERK inhibitor. ASTX029 inhibi
2036272-55-4 | ALC-0315
(Catalog# : 20264)
ALC-0315 is a synthetic cationic lipid (or ionizable lipid). It is a colorless oily m
2055597-12-9 | ASN007
(Catalog# : 20103001)
ASN007 , a novel oral ERK inhibitor , has shown anti-tumor activity in both solid tum
2105904-82-1 | AB-680
(Catalog# : 2091501)
AB-680 is highly potent, reversible and selective CD73 inhibitor. AB680 to be a rever
2230820-11-6 | AZD-7648
(Catalog# : 2071531)
AZD-7648 is a potent and selective DNA-PK inhibitor.
239272-16-1 | AWZ1066S
(Catalog# : 2071530)
AWZ1066S is a highly specific anti-Wolbachia drug candidate for a short-course treatm
2088113-98-6 | AZ31
(Catalog# : 2071508)
AZ31 is a potent and highly selective ATM inhibitor.
2098497-32-4 | (4aS,9bR)-Ethyl 6-bromo-5-(2-(methylamino)-2-oxoethyl)-3,4,4a,5-tetrahydro-1H-pyrido[4,3-b]indole-2(9bH)-carboxylate
(Catalog# : 2062312)
2097416-76-5 | AZD0364
(Catalog# : 206101)
AZD-0364 is a potent and selectiveERK2inhibitor extracted from patent WO2017080979A1,
23687-26-5 | 6-AMINOISOQUINOLINE
(Catalog# : S-203043)
255713-47-4 | A-119637
(Catalog# : 204603)
A-119637 is a novel, selective and potent alpha1D antagonist.
2296729-00-3 | AMG-510
(Catalog# : 112193)
AMG-510 is a potent KRAS G12C covalent inhibitor. AMG-510 selectively targets the KRA
2252403-56-6 | AMG-510 racemate
(Catalog# : 112194)
AMG-510 is a potent KRAS G12C covalent inhibitor. AMG-510 selectively targets the KRA
246529-22-6 | Aramchol
(Catalog# : 6111903)
Galmed Pharmaceuticals Announces Successful Completion of End of Phase 2 Meeting With
2064292-12-0 | A1874
(Catalog# : 193287)
A1874 is a nutlin-based and BRD4-degrading PROTAC which induces BRD4 degradation in c
2196204-23-4 | AZ1495
(Catalog# : 193222)
AZ1495 is a potent and selective IRAK4 inhibitor.
2101291-07-8 | AZD-0284
(Catalog# : 19365)
AZD-0284 is a potent, selective, inverse agonist of the nuclear receptor RORγ for th
202463-68-1 | AM281
(Catalog# : 19315)
AM281 is a synthetic cannabinoid CB1 receptor antagonist.
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
2365193-22-0 | Zelasudil
(Catalog# : 24014)
Zelasudil is a potent, highly selective and orally-active inhibitor that targets Rho-
2134675-36-6 | Ziftomenib ( KO-539 )
(Catalog# : 24013)
Ziftomenib is an oral, potent, and selective small molecule inhibitor that targets th
1640282-42-3 | Zunsemetinib
(Catalog# : 24012)
Zunsemetinib is an investigational oral mitogen-activated protein kinase-activated pr
2728667-27-2 | Zongertinib
(Catalog# : 24011)
Zongertinib [BI 1810631] is a human epidermal growth factor receptor 2 (HER2) inhibit
2272904-53-5 | Zasocitinib
(Catalog# : 24010)
Zasocitinib is under development for the treatment of moderate to severe plaque psori
2503036-46-0 | RNK-05047
(Catalog# : 24008)
RNK-05047 is a PROTAC degrader of BRD4 which displays significant tumor growth inhibi
1001288-58-9 | Asengeprast (FT011)
(Catalog# : 24009)
Asengeprast (FT011) is an anti-fibrotic agent thatreduces mRNA expression of collagen
2490431-16-6 | ERAS-801 ( JGK-068S )
(Catalog# : 20635)
ERAS-801 ( JGK-068S ) is a potent EGFR inhibitor.
209746-59-8 | T-1095
(Catalog# : 24004)
T-1095 is a potent and selective inhibitor of Na+-glucose cotransporters (SGLTs).
2739866-40-9 | NVL-655 ( ALK-IN-27 )
(Catalog# : 24003)
NVL-655 is a novel, brain-penetrant, ALK-selective inhibitor that was designed to add