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PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
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TGF-beta/Smad
DNA Damage
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
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Cas Index 2
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Cas Index 2
2097416-76-5 | AZD0364
(Catalog# : 192275)
AZD0364 is an ERK1 and/or ERK2 kinase for the treatment of cancer. ERK1 and ERK2 kina
2248003-60-1 | AZD3229
(Catalog# : 191287)
AZD3229 is a potent pan-KIT mutant inhibitor for the treatment of gastrointestinal st
2057509-72-3 | AZD4573 free base
(Catalog# : 191212)
AZD-4573 is a selective, short-acting inhibitor of the serine/threonine cyclin-depend
289893-26-1 | Arimoclomol maleate
(Catalog# : 188281)
Arimoclomol, also known as BRX-220, is potentially useful for the treatment of Nieman
22816-60-0 | A22 hydrochloride
(Catalog# : 186211)
A22 is an inhibitor of MreB, an actin-like bacterial protein, and has been shown to a
2095393-15-8 | ARQ-531
(Catalog# : 185176)
ARQ-531 is a potent and orally active BTK inhibitor with potential antineoplastic act
2089288-03-7 | AZD1390
(Catalog# : 18541)
AZD1390 is a potent and selective ATM inhibitor with the ability to cross the blood-b
252017-04-2 | AZD7545
(Catalog# : 179136)
AZD7545 is an inhibitor of pyruvate dehydrogenase kinase 2 (PDHK2) (IC50 value of 6.4
2091134-35-7 | AZD4205
(Catalog# : 20178710)
AZD4205 is a highly potent JAK1-selective kinase inhibitor with excellent preclinical
2002381-31-7 | APS-2-79
(Catalog# : 16122775)
APS-2-79 is a MAPK antagonist that modulating KSR-dependent MAPK signalling by antago
229961-45-9 | AGN 194310
(Catalog# : 6111516)
AGN 194310(VTP-194310) is a potent and selective pan-RARs agonist with Kd values of 3
2002381-25-9 | APS-2-79
(Catalog# : 6111501)
APS-2-79 is an antagonist of MEK phosphorylation by RAF through direct binding of the
21230-50-2 | 3-aMino-1-Methyl-1H-pyrazole-4-carbonitrile
(Catalog# : 6111001)
3-aMino-1-Methyl-1H-pyrazole-4-carbonitrile 21230-50-2
297730-17-7 | AVN944
(Catalog# : 022201)
AVN944 is an orally available, synthetic small molecule with potential antineoplastic
252025-52-8 | Adjudin
(Catalog# : 122824)
Adjudin is a drug which is under development as a potential non-hormonal male contrac
249921-19-5 | Anamorelin
(Catalog# : 122407)
Anamorelin is a synthetic orally active ghrelin receptor agonist which is under devel
23828-92-4 | Ambroxol hydrochloride
(Catalog# : 120408)
Coming soon!
22059-21-8 | 1-aminocyclopropanecarboxylic acid
(Catalog# : 110211)
Coming soon!
256925-03-8 | AL 082D06
(Catalog# : 101921)
AL 082D06(D-06) is the first selective, nonsteroidal glucocorticoid receptor (GR) ant
219766-25-3 | ANA-12
(Catalog# : 101910)
ANA-12 is aTrkB receptor antagonist, which showed direct and selective binding to Trk
2756-85-6 | 1-aminocyclohexane-1-carboxylic acid
(Catalog# : 83110)
Coming soon!
2566-29-2 | 2-amino-2-ethylbutanoic acid
(Catalog# : 83109)
Coming soon!
20776-67-4 | 2-Amino-5-chloro-3-methylbenzoic acid
(Catalog# : 81720)
Coming soon!
2122-63-6 | 4-Amino-3-iodobenzoic acid
(Catalog# : 80311)
Coming soon!
219793-45-0 | AHAS inhibitor
(Catalog# : 52739)
AHAS inhibitor is a novel acetohydroxyacid synthase(AHAS) inhibitor, a promising drug
2627-69-2 | AICAR
(Catalog# : 52702)
AICAR (Acadesine), is an AMP-activated protein kinase activator, which is used for th
2113-51-1 | 1,1'-Biphenyl, 2-iodo-
(Catalog# : 20564)
1,1'-Biphenyl, 2-iodo- is a biochemical.
2513289-74-0 | BSJ-04-122
(Catalog# : 20550)
2095116-40-6 | brigimadlin
(Catalog# : 20533)
Brigimadlin is an E3 ubiquitin-protein ligase Mdm2 inhibitor with potential as an ant
2607829-38-7 | BDTX-1535
(Catalog# : 20512)
BDTX-1535 is a brain-penetrant and potent MasterKey inhibitor of oncogenic mutations
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
1393466-87-9 | PLX8394
(Catalog# : 20613)
PLX8394 is an orally bioavailable inhibitor of serine/threonine-protein kinase B-raf
2365193-22-0 | Zelasudil
(Catalog# : 24014)
Zelasudil is a potent, highly selective and orally-active inhibitor that targets Rho-
2134675-36-6 | Ziftomenib ( KO-539 )
(Catalog# : 24013)
Ziftomenib is an oral, potent, and selective small molecule inhibitor that targets th
1640282-42-3 | Zunsemetinib
(Catalog# : 24012)
Zunsemetinib is an investigational oral mitogen-activated protein kinase-activated pr
2728667-27-2 | Zongertinib
(Catalog# : 24011)
Zongertinib [BI 1810631] is a human epidermal growth factor receptor 2 (HER2) inhibit
2272904-53-5 | Zasocitinib
(Catalog# : 24010)
Zasocitinib is under development for the treatment of moderate to severe plaque psori
2503036-46-0 | RNK-05047
(Catalog# : 24008)
RNK-05047 is a PROTAC degrader of BRD4 which displays significant tumor growth inhibi
1001288-58-9 | Asengeprast (FT011)
(Catalog# : 24009)
Asengeprast (FT011) is an anti-fibrotic agent thatreduces mRNA expression of collagen
2490431-16-6 | ERAS-801 ( JGK-068S )
(Catalog# : 20635)
ERAS-801 ( JGK-068S ) is a potent EGFR inhibitor.
209746-59-8 | T-1095
(Catalog# : 24004)
T-1095 is a potent and selective inhibitor of Na+-glucose cotransporters (SGLTs).