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Apoptosis
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MAPK
Cytoskeletal Signaling
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
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others
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Cas Index 7
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Cas Index 7
778277-15-9 | GNF-5
(Catalog# : 52216)
GNF-5, an analogue of GNF-2 with improved pharmacokinetic properties, is a selective
778270-11-4 | GNF-2
(Catalog# : 52301)
GNF-2 is a highly selective non-ATP competitive inhibitor of oncogenic Bcr-Abl activi
700874-72-2 | Galunisertib(LY2157299)
(Catalog# : 52017)
Galunisertib (LY2157299)isselective TGF- receptor kinase inhibitor. Galunisertib was
703-23-1 | 2'-HYDROXY-6'-METHOXYACETOPHENONE
(Catalog# : 2062006)
7733-96-2 | HC-056456
(Catalog# : 1810171)
HC-056456 is a CatSper channel modulator.
79551-86-3 | 20-HETE
(Catalog# : 185283)
20-HETE is a cytochrome P450 (CYP450) metabolite postulated to play an autacoid role
70500-72-0 | 7-hydroxy-1H-quinolin-2-one
(Catalog# : 91706)
Coming soon!
71759-88-1 | 5-Iodo-1-methyl-1H-imidazole
(Catalog# : 1712292)
5-iodo-1-methylimidazole is a building blocks.
75567-37-2 | Ingenol Mebutate
(Catalog# : 16123020)
Ingenol mebutate, also known as ingenol-3-angelate, is a substance found in the sap o
78919-13-8 | Iloprost
(Catalog# : 16123018)
Iloprost is a drug used to treat pulmonary arterial hypertension (PAH), scleroderma,
775351-65-0 | Imeglimin
(Catalog# : 611811)
Imeglimin(EMD-387008) is the first in a new tetrahydrotriazine-containing class of or
780757-88-2 | ICG-001
(Catalog# : 122801)
ICG-001 is a potent, specific inhibitor of the canonical Wnt signaling pathway in can
761423-87-4 | Ipragliflozin
(Catalog# : 82604)
Ipragliflozin (ASP1941) is a highly potent and selective SGLT2 inhibitor with IC50 of
72795-01-8 | ICI118551(HCl)
(Catalog# : 60809)
Highly selective 2 adrenoceptor antagonist (Ki values are 1.2, 120 and 257 nM at 2, 1
749886-87-1 | JSH-23
(Catalog# : 52729)
JSH-23 is an inhibitor of NF-B transcriptional activity with IC50 of 7.1 M.
796874-99-2 | KYP-2047
(Catalog# : 187124)
KYP-2047 is a very potent, selective inhibitor of Prolyl oligopeptidase (POP), also k
774549-97-2 | KM11060
(Catalog# : 17031301)
KM11060 is a mutated F508del cystic fibrosis transmembrane conductance regulator (CFT
72926-24-0 | K-858
(Catalog# : 16122824)
K-858 is a novel inhibitor of mitotic kinesin Eg5 and antitumor agent, induces cell d
74381-53-6 | Leuprolide Acetate
(Catalog# : 192261)
Leuprolide acetate is the acetate salt of a synthetic nonapeptide analogue of gonadot
700874-71-1 | LY2109761
(Catalog# : 16123039)
LY2109761 is a novel transforming growth factor beta receptor type I and type II dual
79558-09-1 | L-165041
(Catalog# : 011316)
Coming soon!
79794-75-5 | Loratadine
(Catalog# : 010435)
Loratadine is a selective inverse peripheral histamine H1-receptor agonist with an IC
796967-16-3 | Linifanib
(Catalog# : 121416)
Linifanib is a novel, potent ATP-competitive VEGFR/PDGFR inhibitor for KDR, CSF-1R, F
747412-49-3 | Luminespib ( NVP-AUY922 ; VER-52296 )
(Catalog# : 51703)
NVP-AUY922 is an experimental drug candidate for the treatment of cancer. It was disc
706820-79-3 | methyl 3-bromo-5-formyl-4-hydroxybenzoate
(Catalog# : 20363)
794572-10-4 | ML184
(Catalog# : 192214)
CID2440433, also known as ML-184, is a potent synthetic agonist of GPR55 (EC50 = 0.26
78351-75-4 | MY 5445
(Catalog# : 191211)
MY 5445 is a potential platelet aggregation inhibitor.
761438-38-4 | MDK-8384
(Catalog# : 1812254)
MDK-8384, also known as ALK inhibitor 2, is a potent and selective ALK inhibitor.
71203-35-5 | ML-141
(Catalog# : 179152)
ML-141, also known as CID2950007, is a Cdc42 inhibitor (EC50 = 2.1 μM).
70476-82-3 | Mitoxantrone HCl
(Catalog# : 179827)
Mitoxantrone hydrochloride is the hydrochloride salt of an anthracenedione antibiotic
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
2365193-22-0 | Zelasudil
(Catalog# : 24014)
Zelasudil is a potent, highly selective and orally-active inhibitor that targets Rho-
2134675-36-6 | Ziftomenib ( KO-539 )
(Catalog# : 24013)
Ziftomenib is an oral, potent, and selective small molecule inhibitor that targets th
1640282-42-3 | Zunsemetinib
(Catalog# : 24012)
Zunsemetinib is an investigational oral mitogen-activated protein kinase-activated pr
2728667-27-2 | Zongertinib
(Catalog# : 24011)
Zongertinib [BI 1810631] is a human epidermal growth factor receptor 2 (HER2) inhibit
2272904-53-5 | Zasocitinib
(Catalog# : 24010)
Zasocitinib is under development for the treatment of moderate to severe plaque psori
2503036-46-0 | RNK-05047
(Catalog# : 24008)
RNK-05047 is a PROTAC degrader of BRD4 which displays significant tumor growth inhibi
1001288-58-9 | Asengeprast (FT011)
(Catalog# : 24009)
Asengeprast (FT011) is an anti-fibrotic agent thatreduces mRNA expression of collagen
2490431-16-6 | ERAS-801 ( JGK-068S )
(Catalog# : 20635)
ERAS-801 ( JGK-068S ) is a potent EGFR inhibitor.
209746-59-8 | T-1095
(Catalog# : 24004)
T-1095 is a potent and selective inhibitor of Na+-glucose cotransporters (SGLTs).
2739866-40-9 | NVL-655 ( ALK-IN-27 )
(Catalog# : 24003)
NVL-655 is a novel, brain-penetrant, ALK-selective inhibitor that was designed to add