811803-05-1 | Apatinib (Catalog# : 17022301)Apatinib is an orally bioavailable, selective VEGFR2 inhibitor with IC50 of 1 nM. Apatinib (YN968D1) is a novel, orally bioavailable, selective inhibitor with potential antiang
878385-84-3 | AZD-5069 (Catalog# : 16122864)AZD-5069 is a potent and selective CXCR2 antagonist with the potential to inhibit neutrophil migration into the airways in patients with COPD. AZD-5069 was shown to inhibit bindi
870281-34-8 | Acalisib (Catalog# : 16071413)Acalisib, also known as GS-9820, is an inhibitor of the beta and delta isoforms of the 110 kDa catalytic subunit of class IA phosphoinositide-3 kinases (PI3K) with potential immu
865305-30-2 | AF-353 (Catalog# : 16071021)AF-353 is a novel, potent and orally bioavailable P2X3/P2X2/3 receptor antagonist, inhibits human and rat P2X3 (pIC50= 8.0). IC50 value: pIC50 = 8.0 (pIC50, for P2X3) Target: P2X
897383-62-9 | AST-1306 (Catalog# : 122926)AST-1306 is a novel irreversible inhibitor of EGFR and ErbB2 with IC50 of 0.5 nM and 3 nM, also effective in mutation EGFR T790M/L858R, more potent to ErbB2-overexpressing cells,
896466-04-9 | AT9283 (Catalog# : 52769)AT9283 is a small molecule a multi-targeted inhibitor with IC50s of 4, 1.2, 1.1 and approximate 3 nM for Bcr-Abl(T3151), JAK2 and JAK3, Aurora A and Aurora B, respectively.
850140-72-6 | Afatinib (Catalog# : 52719)Afatinib (BIBW2992) irreversibly inhibits EGFR/HER2 including EGFR(wt), EGFR(L858R), EGFR(L858R/T790M) and HER2 with IC50 of 0.5 nM, 0.4 nM, 10 nM and 14 nM, respectively; 100-fo
852808-04-9 | ABT-737 (Catalog# : 52640)ABT-737 is a BH3 mimetic inhibitor ofBcl-xL,Bcl-2andBcl-wwithEC50of 78.7 nM, 30.3 nM and 197.8 nM in cell-free assays, respectively; no inhibition observed against Mcl-1, Bcl-B o
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