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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
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GPCR & G Protein
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Cas Index 8
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Cas Index 8
877387-37-6 (free base) | GSK5182
(Catalog# : 20375)
GSK5182 is a specific inverse agonist for estrogen-related receptor γ.
881639-98-1 | G-1
(Catalog# : 206103)
G-1 is a selective agonist for GPER. It acts by blocking tubulin polymerization.
827319-43-7 | GW-870086
(Catalog# : 1811263)
GW-870086 is a glucocorticoid receptor agonist potentially for the treatment of asthm
880635-03-0 | GW6471
(Catalog# : 181151)
GW6471 is a PPAR α antagonist (IC50 = 0.24 μ M). GW6471 enhances the binding affini
817194-38-0 | GSK180736A (GSK180736)
(Catalog# : 178901)
GSK180736A is potent and selective inhibitor of GRK2 with an IC50 of 0.77 M25 and >10
844903-58-8 | GSK163090
(Catalog# : 6111015)
GSK163090 is a potent, selective, and orally active 5-HT1A/B/D receptor antagonist wi
863513-91-1 | GRT-6005
(Catalog# : 16071110)
Cebranopadol is a potent nociceptin/orphanin FQ peptide (NOP) and opioid receptor ago
873652-48-3 | GDC-0152
(Catalog# : 16071101)
GDC-0152 is a second mitochondrial activator of caspases (Smac) mimetic inhibitor of
839706-07-9 | GNF-7
(Catalog# : 16060604)
BenzaMide
870483-87-7 | GW2580
(Catalog# : 122524)
GW2580 is an orally bioavailable inhibitor of c-FMS kinase; completely inhibited huma
850664-21-0 | GSK269962A
(Catalog# : 102206)
GSK269962A(CAS 850664-21-0) is a potent ROCK inhibitor (IC50 values are 1.6 and 4 nM
851983-85-2 | Galeterone
(Catalog# : 62003)
Galeterone(VN/124-1,TOK001) is a highly selective, multi-targeted, oral small molecul
864082-47-3 | GSK429286A
(Catalog# : 52629)
GSK429286A is a selective inhibitor of ROCK1 and ROCK2 with IC50 of 14 nM and 63 nM,
888216-25-9 | Ganetespib(STA-9090)
(Catalog# : 52021)
Ganetespib blocked the ability of HSP90 to bind to biotinylated geldanamycin and disr
851870-24-1 | 4-iodo-2-isopropyl-1-Methyl-1H-iMidazole
(Catalog# : 2062023)
887401-93-6 | INCB3284 mesylate
(Catalog# : 191143)
INCB3284 is a potent, selective, and orally bioavailable hCCR2 Antagonist.
835619-41-5 | Indeglitazar
(Catalog# : 1812131)
Indeglitazar, also known as PPM-204 and PLX-204, is an orally available peroxisome pr
832115-62-5 | ISX-9
(Catalog# : 17022713)
ISX-9 is a neurogenic agent. Isx-9 promotes neurogenesis in vivo, enhancing the proli
873225-46-8 | IKK-16
(Catalog# : 16123017)
IKK-16 is a potent and slective inhibitor of IB kinase (IKK) (IC50 values are 40, 70
866927-10-8 | IC87201
(Catalog# : 16122820)
IC87201 is a nNOS-PDZ/PSD-95-PDZ inhibitor. IC87201 showed great promise in cellular
851870-28-5 | 5-Iodo-2-isopropyl-1-methyl-1H-imidazole
(Catalog# : 021701)
Coming soon!
857679-55-1 | INCB8761 (PF-4136309)
(Catalog# : 92210)
INCB8761(PF-4136309) is a potent, selective, and orally bioavailable CCR2 antagonist.
879-37-8 | Indole-3-Acetamide
(Catalog# : 81920)
Coming soon!
873054-44-5 | Ivacaftor
(Catalog# : 52805)
Ivacaftor (VX-770) is a potentiator of CFTR targeting G551D-CFTR and F508del-CFTR wit
878489-28-2 | JNJ 303
(Catalog# : 122938)
Coming soon!
881202-45-5 | JNJ-26854165 (Serdemetan)
(Catalog# : 52522)
JNJ-26854165 (Serdemetan) acts as a HDM2 ubiquitin ligase antagonist and also induces
888032-58-4 | KPI-10
(Catalog# : 20277)
KPI-10 is a new compound currently being studied for its efficacy in the treatment of
845932-30-1 | KU59403
(Catalog# : 19123)
KU59403 is a potent and selective ATM (Ataxia telangiectasia mutated) inhibitor with
853299-07-7 | K03861
(Catalog# : 611921)
K03861 is a type II CDK2 inhibitor with Kd of 8.2 nM.K03861 inhibits CDK2 activity by
819812-04-9 | KW-2478
(Catalog# : 121431)
KW-2478 is an agent that targets the human heat-shock protein 90 (Hsp90) with potenti
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
2365193-22-0 | Zelasudil
(Catalog# : 24014)
Zelasudil is a potent, highly selective and orally-active inhibitor that targets Rho-
2134675-36-6 | Ziftomenib ( KO-539 )
(Catalog# : 24013)
Ziftomenib is an oral, potent, and selective small molecule inhibitor that targets th
1640282-42-3 | Zunsemetinib
(Catalog# : 24012)
Zunsemetinib is an investigational oral mitogen-activated protein kinase-activated pr
2728667-27-2 | Zongertinib
(Catalog# : 24011)
Zongertinib [BI 1810631] is a human epidermal growth factor receptor 2 (HER2) inhibit
2272904-53-5 | Zasocitinib
(Catalog# : 24010)
Zasocitinib is under development for the treatment of moderate to severe plaque psori
2503036-46-0 | RNK-05047
(Catalog# : 24008)
RNK-05047 is a PROTAC degrader of BRD4 which displays significant tumor growth inhibi
1001288-58-9 | Asengeprast (FT011)
(Catalog# : 24009)
Asengeprast (FT011) is an anti-fibrotic agent thatreduces mRNA expression of collagen
2490431-16-6 | ERAS-801 ( JGK-068S )
(Catalog# : 20635)
ERAS-801 ( JGK-068S ) is a potent EGFR inhibitor.
209746-59-8 | T-1095
(Catalog# : 24004)
T-1095 is a potent and selective inhibitor of Na+-glucose cotransporters (SGLTs).
2739866-40-9 | NVL-655 ( ALK-IN-27 )
(Catalog# : 24003)
NVL-655 is a novel, brain-penetrant, ALK-selective inhibitor that was designed to add