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PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
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DNA Damage
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
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GPCR & G Protein
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Cas Index 8
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Cas Index 8
878672-00-5 | Lesinurad
(Catalog# : 17022706)
Lesinurad(RDEA594), once-daily inhibitor of URAT1, is a transporter in the kidney tha
892128-60-8 | LY2334737
(Catalog# : 16123040)
LY2334737 is an orally available valproic acid ester of gemcitabine, a broad-spectrum
847871-99-2 | Lenalidomide hemihydrate
(Catalog# : 6111409)
Lenalidomide (Revlimid, CC-5013) is a TNF- secretion inhibitor with IC50 of 13 nM.Len
867160-71-2 | Linsitinib
(Catalog# : 010819)
Linsitinib is highly potent, orally efficacious and highly selective, dual ATP-compet
862507-23-1 | LY2228820
(Catalog# : 122509)
LY2228820 is a novel and potent p38MAPK inhibitor (the IC50 for p38MAPK and p38MAPK w
846589-98-8 | Lorcaserin Hydrochloride
(Catalog# : 52721)
Lorcaserin HCl(APD-356 Hcl) is a selective full agonist of human 5-HT2C receptor with
891016-02-7 | ML-SI3
(Catalog# : 20287)
ML-SI3 is a chemical compound which acts as an "antagonist" (i.e. channel b
838810-96-1 | MAC-545496
(Catalog# : 2071611)
MAC-545496 is potent GraR inhibitor (glycopeptide-resistance-associated protein R). M
877636-42-5 | ML221
(Catalog# : 19311)
ML221 is an antagonist of the apelin (APJ) receptor.
869901-69-9 | MK-2048
(Catalog# : 181251)
MK-2048 is a a second-generation HIV-1 integrase inhibitor.
847163-28-4 | ML 351
(Catalog# : 1811282)
ML 351 is a selective 12/15 LOX inhibitor that is active in vivo.
869363-13-3 | MLN8054
(Catalog# : 18742)
MLN8054 is an aurora kinase inhibitor MLN8054, which is an orally bioavailable, highl
825658-06-8 | ML335
(Catalog# : 184216)
ML335是一种有效的、选择性的TREK-1/2激活剂。ML335是一种用于OPRM1-O
846557-71-9 | ML-385
(Catalog# : 179119)
ML-385 is a potent and selective NRF2 inhibitor (Nrf2; IC50 = 1.9 μM) . ML-385 selec
878978-76-8 | ML-098
(Catalog# : 17030910)
ML-098, also known as CID-7345532, is an activator of the GTP-binding protein Rab7 (E
899713-86-1 | ML348
(Catalog# : 17030712)
ML348, also known as CID 3238952; SID 160654487, is a reversible LYPLA1 inhibitor wit
863971-19-1 | Mafodotin
(Catalog# : 16122831)
Mafodotin, also known as mc-MMAF and SGD-1269 or Maleimidocaproyl monomethylauristati
862189-95-5 | Mirodenafil
(Catalog# : 030904)
Coming soon!
897657-95-3 | MSX-122
(Catalog# : 011906)
MSX-122 is a n orally bioavailable inhibitor of CXCR4 with potential antineoplastic a
852536-39-1 | ME-143
(Catalog# : 011902)
ME -143 is a derivative of triphendiol and is a highly potent, pan acting ant-cancer.
86347-15-1 | Medetomidine hydrochloride
(Catalog# : 010606)
Medetomidine Hydrochloride is an agonist of adrenergic alpha-2 receptor, which is use
870005-19-9 | MK-2048
(Catalog# : 010424)
MK-2048 is a second generation integrase inhibitor, intended to be used against HIV i
885325-71-3 | MK8745
(Catalog# : 122819)
MK-8745 is a novel Aurora-A specific inhibitor. MK8745 induced apoptotic cell death i
875337-44-3 | MGCD-265-analog
(Catalog# : 111013)
MGCD-265-analog is a tyrosine kinase inhibitor that selectively targets MET and Axl.M
88191-84-8 | MDL 28170
(Catalog# : 102610)
MDL 28170 is a potent, cell-permeable, and selective inhibitor of calpain and catheps
85278-24-6 | MDL72274(HCl)
(Catalog# : 90301A)
MDL72274 is a specific semicarbazide-sensitive amine oxidase (SSAO) inhibitor.
857876-30-3 | Motesanib Diphosphate (AMG-706)
(Catalog# : 52101)
Motesanib Diphosphate (AMG-706) is a potent ATP-competitive inhibitor ofVEGFR1/2/3wit
81624-55-7 | NSC348884
(Catalog# : 20487)
NSC348884 is a nucleophosmin inhibitor. NSC348884 also disrupts oligomer formation an
83366-66-9 | Nefazodone
(Catalog# : 20463)
Nefazodone is an antidepressant. Its chemical structure is unrelated to selective ser
882272-97-1 | N,N-dibenzyl-6-chloro-5-nitropyrimidine-4-amine
(Catalog# : 2062033)
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
1393466-87-9 | PLX8394
(Catalog# : 20613)
PLX8394 is an orally bioavailable inhibitor of serine/threonine-protein kinase B-raf
2365193-22-0 | Zelasudil
(Catalog# : 24014)
Zelasudil is a potent, highly selective and orally-active inhibitor that targets Rho-
2134675-36-6 | Ziftomenib ( KO-539 )
(Catalog# : 24013)
Ziftomenib is an oral, potent, and selective small molecule inhibitor that targets th
1640282-42-3 | Zunsemetinib
(Catalog# : 24012)
Zunsemetinib is an investigational oral mitogen-activated protein kinase-activated pr
2728667-27-2 | Zongertinib
(Catalog# : 24011)
Zongertinib [BI 1810631] is a human epidermal growth factor receptor 2 (HER2) inhibit
2272904-53-5 | Zasocitinib
(Catalog# : 24010)
Zasocitinib is under development for the treatment of moderate to severe plaque psori
2503036-46-0 | RNK-05047
(Catalog# : 24008)
RNK-05047 is a PROTAC degrader of BRD4 which displays significant tumor growth inhibi
1001288-58-9 | Asengeprast (FT011)
(Catalog# : 24009)
Asengeprast (FT011) is an anti-fibrotic agent thatreduces mRNA expression of collagen
2490431-16-6 | ERAS-801 ( JGK-068S )
(Catalog# : 20635)
ERAS-801 ( JGK-068S ) is a potent EGFR inhibitor.
209746-59-8 | T-1095
(Catalog# : 24004)
T-1095 is a potent and selective inhibitor of Na+-glucose cotransporters (SGLTs).