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Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
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Building Blocks
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Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
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Pyridines
Pyrimidines
Quinolines
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On Sale
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
Building Blocks
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
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On Sale
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Custom Synthesis
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Name Index A
ARS-853
(Catalog# : 16070910, Cas# :
1629268-00-3
)
ARS-853 is a selective, covalent inhibitor of KRAS-G12C that inhibits mutant KRAS dri
Asunaprevir
(Catalog# : 16070810, Cas# :
630420-16-5
)
Asunaprevir, also known as BMS-650032, is an inhibitor of the hepatitis C virus enzym
AZD2281(Olaparib)
(Catalog# : 92801, Cas# :
763113-22-0
)
Olaparib (AZD-2281, trade name Lynparza) is an FDA-approved targeted therapy for canc
AZ91498
(Catalog# : 16070801, Cas# :
773871-93-5
)
AZ91498
A-769662
(Catalog# : 16070701, Cas# :
844499-71-4
)
A-769662 is a potent, reversible AMP-activated protein kinase (AMPK) activator with a
AM-580
(Catalog# : 16062701, Cas# :
102121-60-8
)
AM-580 is a potent RARalpha agonist. AM580 has powerful and selective cyto-differenti
Aurora A Inhibitor I
(Catalog# : 16062401, Cas# :
1158838-45-9
)
Aurora A Inhibitor I
AN-2718
(Catalog# : 16062104, Cas# :
174672-06-1
)
AN-2718
AZ7371
(Catalog# : 16062102, Cas# :
1494675-86-3
)
AZ7371 is a a novel non-covalent DprE1 inhibitor
Amcinafide
(Catalog# : 16062001, Cas# :
7332-27-6
)
Amcinafide
AZD-3965
(Catalog# : 33001, Cas# :
1448671-31-5
)
AZD3965 is a selective inhibitor of monocarboxylate transporter 1 (MCT1) with a bindi
AVN944
(Catalog# : 022201, Cas# :
297730-17-7
)
AVN944 is an orally available, synthetic small molecule with potential antineoplastic
Arry-380
(Catalog# : 021801, Cas# :
937265-83-3
)
ARRY-380 is a potent and selective HER2 inhibitor with IC50 of 8 nM, equipotent again
A-1331852
(Catalog# : 012603, Cas# :
1430844-80-6
)
Coming soon!
A-1155463
(Catalog# : 012602, Cas# :
1235034-55-5
)
A-1155463 is a highly potent and selective BCL-XL inhibitor.
AH13205
(Catalog# : 011919, Cas# :
148436-63-9
)
Coming soon!
Alofanib
(Catalog# : 011918, Cas# :
1612888-66-0
)
Alofanib is a potential small molecule kinase inhibitor with potential anticancer act
AS 602801
(Catalog# : 011913, Cas# :
848344-36-5
)
AS 602801 is a novel, orally active inhibitor of JNK.
AMG232
(Catalog# : 011911, Cas# :
1352066-68-2
)
AMG232 is an extremely potent MDM2 inhibitor (SPR KD = 0.045 nM, SJSA-1 EdU IC50 = 9.
Afdx 384
(Catalog# : 011905, Cas# :
118290-27-0
)
Coming soon!
Avoralstat
(Catalog# : 011813, Cas# :
918407-35-9
)
Avoralstat (formerly BCX4161) is a potent small-molecule oral plasma kallikrein inhib
AMG-337
(Catalog# : 01181, Cas# :
1173699-31-4
)
AMG-337 is a potent and highly selective small molecule ATP-competitive MET kinase in
Afuresertib
(Catalog# : 011811, Cas# :
1047644-62-1
)
Afuresertib is a potent pan-AKT inhibitor that demonstrated synergy with bortezomib i
AMG 900
(Catalog# : 011803, Cas# :
945595-80-2
)
AMG 900 is a potent and highly selective pan-Aurora kinases inhibitor for Aurora A/B/
APTO-253
(Catalog# : 011802, Cas# :
1422731-37-0
)
APTO-253 is a small molecule inhibitor of human metal-regulatory transcription factor
AC-55541
(Catalog# : 011302, Cas# :
916170-19-9
)
AC-55541 is a novel small-molecule protease-activated receptor 2(PAR2) agonist.
AZ 628
(Catalog# : 011120, Cas# :
878739-06-1
)
AZ628 is a new pan-Raf inhibitor for BRAF, BRAFV600E, and c-Raf-1 with IC50 of 105 nM
AZD-5582
(Catalog# : 011117, Cas# :
1258392-53-8
)
AZD5582 is a potent IAP inhibitor, which is a dimeric compound based on the AVPI moti
Arbidol hydrochloride
(Catalog# : 011111, Cas# :
131707-23-8
)
Arbidol is an broad-spectrum antiviral chemical agent which can inhibit cell entry of
APY29
(Catalog# : 011108, Cas# :
1216665-49-4
)
APY29 is an allosteric modulator of IRE1; inhibits IRE1 autophosphorylation (IC50 = 2
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
PLX8394
(Catalog# : 20613, Cas# :
1393466-87-9
)
PLX8394 is an orally bioavailable inhibitor of serine/threonine-protein kinase B-raf
Zelasudil
(Catalog# : 24014, Cas# :
2365193-22-0
)
Zelasudil is a potent, highly selective and orally-active inhibitor that targets Rho-
Ziftomenib ( KO-539 )
(Catalog# : 24013, Cas# :
2134675-36-6
)
Ziftomenib is an oral, potent, and selective small molecule inhibitor that targets th
Zunsemetinib
(Catalog# : 24012, Cas# :
1640282-42-3
)
Zunsemetinib is an investigational oral mitogen-activated protein kinase-activated pr
Zongertinib
(Catalog# : 24011, Cas# :
2728667-27-2
)
Zongertinib [BI 1810631] is a human epidermal growth factor receptor 2 (HER2) inhibit
Zasocitinib
(Catalog# : 24010, Cas# :
2272904-53-5
)
Zasocitinib is under development for the treatment of moderate to severe plaque psori
RNK-05047
(Catalog# : 24008, Cas# :
2503036-46-0
)
RNK-05047 is a PROTAC degrader of BRD4 which displays significant tumor growth inhibi
Asengeprast (FT011)
(Catalog# : 24009, Cas# :
1001288-58-9
)
Asengeprast (FT011) is an anti-fibrotic agent thatreduces mRNA expression of collagen
ERAS-801 ( JGK-068S )
(Catalog# : 20635, Cas# :
2490431-16-6
)
ERAS-801 ( JGK-068S ) is a potent EGFR inhibitor.
T-1095
(Catalog# : 24004, Cas# :
209746-59-8
)
T-1095 is a potent and selective inhibitor of Na+-glucose cotransporters (SGLTs).