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Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
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Immunology & Inflammation
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Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
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Indoles and Oxindoles
Iodos
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Oxazoles
Peg Linkers
Phenols
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
Building Blocks
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
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Other Azoles
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Name Index A
Abivertinib
(Catalog# : 19141, Cas# :
1557267-42-1
)
Abivertinib, also known as AC0010 and Avitinib, is a tyrosine kinase inhibitor, antin
AZD7507
(Catalog# : 1812294, Cas# :
1041852-85-0
)
AZD7507 is a potent and selective CSF-1R inhibitor (32 nM cell activity), AZD7507 is
Auranofin
(Catalog# : 1812281, Cas# :
34031-32-8
)
Auranofin, also known as Ridaura and SKF-39162, is an oral chrysotherapeutic agent fo
AX-024 HCl
(Catalog# : 181254, Cas# :
1704801-24-0
)
AX-024 is an orally available inhibitor of the TCR-Nck interaction that selectively i
AG 879
(Catalog# : 1811303, Cas# :
148741-30-4
)
AG-879 is a tyrphostin compound that inhibits nerve growth factor-dependent TrkA tyro
Avagacestat
(Catalog# : 1811283, Cas# :
1146699-66-2
)
Avagacestat, also known as BMS-708163, is an oral GSI designed for selective inhibiti
AS1842856
(Catalog# : 1811265, Cas# :
836620-48-5
)
AS1842856 is a cell-permeable Foxo1inhibitor that blocks the transcription activity o
Anlotinib HCl ( AL-3818 )
(Catalog# : 1811211, Cas# :
1360460-82-7
)
Anlotinib is a novel oral tyrosine kinase inhibitor (TKI) targeting c-kit, platelet-d
Avatrombopag maleate
(Catalog# : 5141902, Cas# :
677007-74-8
)
Avatrombopag maleate is an orally bioavailable, small molecule thrombopoietin recepto
AZD-3514
(Catalog# : 1810251, Cas# :
1240299-33-5
)
AZD-3514 is a potent androgen receptor downregulator with potential anticancer cancer
AZ32
(Catalog# : 1810223, Cas# :
no
)
AZ32 is an orally bioavailable and blood-brain barrier-penetrating ATM inhibitor with
ARS-1620
(Catalog# : 1810222, Cas# :
1698055-85-4
)
ARS-1620 is an atropisomeric selective KRAS-G12C inhibitor with desirable pharmacokin
AGL-2263
(Catalog# : 1810175, Cas# :
638213-98-6
)
AGL-2263 is a novel insulin receptor inhibitor.
AM211
(Catalog# : 1810173, Cas# :
1175526-27-8
)
AM-211 is a novel and potent antagonist of the prostaglandin D2 receptor type 2.
Arimoclomol maleate
(Catalog# : 188281, Cas# :
289893-26-1
)
Arimoclomol, also known as BRX-220, is potentially useful for the treatment of Nieman
ASP7663
(Catalog# : 187123, Cas# :
1190217-35-6
)
ASP7663 is an orally bioavailable selective TRPA1 activator.
Aldoxorubicin HCl
(Catalog# : 187111, Cas# :
480998-12-7
)
Aldoxorubicin, also known as INNO-206 and Doxo-EMCH, is the 6-maleimidocaproyl hydraz
ABT 702 Dihydrochloride
(Catalog# : 18791, Cas# :
1188890-28-9
)
ABT 702 Dihydrochloride is a potent non-nucleoside adenosine kinase inhibitor, select
Avacopan
(Catalog# : 18761, Cas# :
1346623-17-3
)
Avacopan, also known as CCX168, is an orally active, selective and potent C5aR inhibi
AEW-541
(Catalog# : 18753, Cas# :
475489-16-8
)
AEW541, also known as NVP-AEW541, is a novel, potent IGF-IR kinase inhibitor.
AMD-070 HCl
(Catalog# : 18741, Cas# :
880549-30-4
)
AMD11070, also known as AMD070, X4P-001 and mavorixafor, is an orally bioavailable an
AG-494
(Catalog# : 186273, Cas# :
133550-35-3
)
AG-494, also known as Tyrphostin AG-494, is an inhibitor of epidermal growth factor r
AZD5153
(Catalog# : 186254, Cas# :
1869912-39-9
)
AZD5153 is a potent bivalent triazolopyridazine based Bromodomain and Extraterminal (
Amenamevir
(Catalog# : 186252, Cas# :
841301-32-4
)
Amenamevir, also known as ASP2151, is a herpes virus helicase-primase inhibitor.
A22 hydrochloride
(Catalog# : 186211, Cas# :
22816-60-0
)
A22 is an inhibitor of MreB, an actin-like bacterial protein, and has been shown to a
AST487
(Catalog# : 186158, Cas# :
630124-46-8
)
AST487, also known as NVP- AST487, is a RET kinase inhibitor/FLT3 inhibitor.
ARV-825
(Catalog# : 185253, Cas# :
1818885-28-7
)
ARV-825 is a PROTAC (proteolysis-targeting chimera). ARV-825 exerts superior lethal a
Alobresib
(Catalog# : 185222, Cas# :
1637771-14-2
)
Alobresib is an antineoplastic drug candidate.
Adavivint
(Catalog# : 185221, Cas# :
1467013-03-3
)
Adavivint is a Wnt pathway inhibitor and immunomodulator drug candidate.
ALX 1393
(Catalog# : 185213, Cas# :
949164-09-4
)
ALX 1393 is a glycine transporter-2 inhibitor.
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
PLX8394
(Catalog# : 20613, Cas# :
1393466-87-9
)
PLX8394 is an orally bioavailable inhibitor of serine/threonine-protein kinase B-raf
Zelasudil
(Catalog# : 24014, Cas# :
2365193-22-0
)
Zelasudil is a potent, highly selective and orally-active inhibitor that targets Rho-
Ziftomenib ( KO-539 )
(Catalog# : 24013, Cas# :
2134675-36-6
)
Ziftomenib is an oral, potent, and selective small molecule inhibitor that targets th
Zunsemetinib
(Catalog# : 24012, Cas# :
1640282-42-3
)
Zunsemetinib is an investigational oral mitogen-activated protein kinase-activated pr
Zongertinib
(Catalog# : 24011, Cas# :
2728667-27-2
)
Zongertinib [BI 1810631] is a human epidermal growth factor receptor 2 (HER2) inhibit
Zasocitinib
(Catalog# : 24010, Cas# :
2272904-53-5
)
Zasocitinib is under development for the treatment of moderate to severe plaque psori
RNK-05047
(Catalog# : 24008, Cas# :
2503036-46-0
)
RNK-05047 is a PROTAC degrader of BRD4 which displays significant tumor growth inhibi
Asengeprast (FT011)
(Catalog# : 24009, Cas# :
1001288-58-9
)
Asengeprast (FT011) is an anti-fibrotic agent thatreduces mRNA expression of collagen
ERAS-801 ( JGK-068S )
(Catalog# : 20635, Cas# :
2490431-16-6
)
ERAS-801 ( JGK-068S ) is a potent EGFR inhibitor.
T-1095
(Catalog# : 24004, Cas# :
209746-59-8
)
T-1095 is a potent and selective inhibitor of Na+-glucose cotransporters (SGLTs).