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Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
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Building Blocks
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Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
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Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
Building Blocks
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
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Custom Synthesis
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Name Index I
INX 08189
(Catalog# : 186253, Cas# :
1234490-83-5
)
INX 08189 is an RNA-directed RNA polymerase (NS5B) inhibitor potentially for the trea
IWP-O1
(Catalog# : 186222, Cas# :
2074607-48-8
)
IWP-O1 is highly potent Porcn inhibitor, is essential for the secretion of Wnt protei
INCB057643
(Catalog# : 185232, Cas# :
1820889-23-3
)
INCB057643 is a BET inhibitor. INCB054329 reduces homologous recombination efficiency
Iberdomide
(Catalog# : 185216, Cas# :
1323403-33-3
)
Iberdomide, also known as CC-220, is potentially for the treatment of systemic lupus
INCB3344
(Catalog# : 185215, Cas# :
1262238-11-8
)
INCB3344 is a potent and selective antagonist of CCR2 receptor with IC(50) values of
iCRT3
(Catalog# : 18492, Cas# :
901751-47-1
)
iCRT3 is an inhibitor of the Wnt/wingless signaling pathway. iCRT3 efficiently block
IDO-IN-2
(Catalog# : 184317, Cas# :
1668565-74-9
)
IDO inhibitor 1 is a potent inhibitor of IDO (indoleamine-(2,3)-dioxygenase) with IC5
IPI-3063
(Catalog# : 18433, Cas# :
1425043-73-7
)
IPI-3063 is a Selective Phosphoinoside-3-Kinase p110δ Inhibitor. IPI-3063 Potently S
5-Iodo-1-methyl-1H-imidazole
(Catalog# : 1712292, Cas# :
71759-88-1
)
5-iodo-1-methylimidazole is a building blocks.
6-(4-isopropyl-4H-1,2,4-triazol-3-yl)pyridin-2-amine
(Catalog# : 1710123, Cas# :
1448427-99-3
)
6-(4-isopropyl-4H-1,2,4-triazol-3-yl)pyridin-2-amine
IDRA-21
(Catalog# : 179134, Cas# :
22503-72-6
)
IDRA-21 is a positive AMPA receptor modulator. IDRA-21 inhibits synaptic and extrasyn
ISCK03
(Catalog# : 1791118, Cas# :
945526-43-2
)
ISCK03 is a potent c-kit inhibitor. ISCK03 inhibits SCF/c-kit signaling in 501mel hum
IACS-9571
(Catalog# : 1783019, Cas# :
1800477-30-8
)
IACS-9571 is a potent and selective inhibitor TRIM24 and BRPF1. The bromodomain conta
Importazole
(Catalog# : 17031013, Cas# :
662163-81-7
)
Importazole is a small molecule inhibitor of the transport receptor importin- speci
IDE1
(Catalog# : 17030309, Cas# :
1160927-48-9
)
IDE1 is a potent cell-permeable definitive endoderm formation inducer (EC50 = 125 nM,
ISX-9
(Catalog# : 17022713, Cas# :
832115-62-5
)
ISX-9 is a neurogenic agent. Isx-9 promotes neurogenesis in vivo, enhancing the proli
Ixazomib (MLN-2238)
(Catalog# : 16123024, Cas# :
1072833-77-2
)
Ixazomib, also known as MLN-2238, is a potent proteasome inhibitor (PI) with potentia
Isovaleramide
(Catalog# : 16123023, Cas# :
541-46-8
)
Isovaleramide, also known as NPS-1776, is a drug potentially for the treatment of mig
Isosorbide Mononitrate
(Catalog# : 16123022, Cas# :
16051-77-7
)
Isosorbide Mononitrate is a drug used principally in the treatment of angina pectoris
IQ-1S
(Catalog# : 16123021, Cas# :
23146-22-7
)
IQ-1S is a potent and selective c-Jun N-Terminal Kinase Inhibitor. IQ-1S inhibits mur
Ingenol Mebutate
(Catalog# : 16123020, Cas# :
75567-37-2
)
Ingenol mebutate, also known as ingenol-3-angelate, is a substance found in the sap o
Imperatorin
(Catalog# : 16123019, Cas# :
482-44-0
)
Imperatorin, aslo known as Pentosalen, Marmelosin, is a furocoumarin and a phytochemi
Iloprost
(Catalog# : 16123018, Cas# :
78919-13-8
)
Iloprost is a drug used to treat pulmonary arterial hypertension (PAH), scleroderma,
IKK-16
(Catalog# : 16123017, Cas# :
873225-46-8
)
IKK-16 is a potent and slective inhibitor of IB kinase (IKK) (IC50 values are 40, 70
IDO-IN-1
(Catalog# : 16122822, Cas# :
914638-30-5
)
IDO-IN-1 is a potent and selective indoleamine-2,3-dioxygenase (IDO) inhibitor with I
Idalopirdine (Lu AE58054)
(Catalog# : 16122821, Cas# :
467459-31-0
)
Idalopirdine, also known as Lu AE58054 or Iladopirdine, is a potent and selective 5-H
IC87201
(Catalog# : 16122820, Cas# :
866927-10-8
)
IC87201 is a nNOS-PDZ/PSD-95-PDZ inhibitor. IC87201 showed great promise in cellular
ITSA-1 (ITSA1)
(Catalog# : 16122741, Cas# :
200626-61-5
)
ITSA-1 (ITSA1) is an HDAC activator via TSA suppression, but shows no activity toward
5-Iodotubercidin
(Catalog# : 16122729, Cas# :
24386-93-4
)
5-Iodotubercidin is a potent adenosine kinase inhibitor with IC50 of 26 nM. It inhibi
IMR-1A
(Catalog# : 6111507, Cas# :
331862-41-0
)
IMR-1A is the metabolite of IMR-1. IMR-1 is a novel class of Notch inhibitors targeti
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
Zelasudil
(Catalog# : 24014, Cas# :
2365193-22-0
)
Zelasudil is a potent, highly selective and orally-active inhibitor that targets Rho-
Ziftomenib ( KO-539 )
(Catalog# : 24013, Cas# :
2134675-36-6
)
Ziftomenib is an oral, potent, and selective small molecule inhibitor that targets th
Zunsemetinib
(Catalog# : 24012, Cas# :
1640282-42-3
)
Zunsemetinib is an investigational oral mitogen-activated protein kinase-activated pr
Zongertinib
(Catalog# : 24011, Cas# :
2728667-27-2
)
Zongertinib [BI 1810631] is a human epidermal growth factor receptor 2 (HER2) inhibit
Zasocitinib
(Catalog# : 24010, Cas# :
2272904-53-5
)
Zasocitinib is under development for the treatment of moderate to severe plaque psori
RNK-05047
(Catalog# : 24008, Cas# :
2503036-46-0
)
RNK-05047 is a PROTAC degrader of BRD4 which displays significant tumor growth inhibi
Asengeprast (FT011)
(Catalog# : 24009, Cas# :
1001288-58-9
)
Asengeprast (FT011) is an anti-fibrotic agent thatreduces mRNA expression of collagen
ERAS-801 ( JGK-068S )
(Catalog# : 20635, Cas# :
2490431-16-6
)
ERAS-801 ( JGK-068S ) is a potent EGFR inhibitor.
T-1095
(Catalog# : 24004, Cas# :
209746-59-8
)
T-1095 is a potent and selective inhibitor of Na+-glucose cotransporters (SGLTs).
NVL-655 ( ALK-IN-27 )
(Catalog# : 24003, Cas# :
2739866-40-9
)
NVL-655 is a novel, brain-penetrant, ALK-selective inhibitor that was designed to add