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Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
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TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
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GPCR & G Protein
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Bromides
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Fluorides
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Indoles and Oxindoles
Iodos
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Peg Linkers
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
Building Blocks
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
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Other Azoles
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Name Index L
Leukadherin-1
(Catalog# : 161227107, Cas# :
344897-95-6
)
Leukadherin-1 (LA1) is a small molecule agonist that enhances CD11b/CD18-dependent ce
Ledipasvir (GS5885)
(Catalog# : 16122765, Cas# :
1256388-51-8
)
Ledipasvir (GS5885) is a HCV NS5A polymerase inhibitor, used for the treatment of hep
LLY-507
(Catalog# : 16122739, Cas# :
1793053-37-8
)
LLY-507 is a cell-active, potent, and selective inhibitor of protein-lysine Methyltra
Lirametostat ( CPI-1205 )
(Catalog# : 16122736, Cas# :
1621862-70-1
)
Lirametostat ( CPI-1205 ) is a potent, selective, and cofactor-competitive inhibitor
L755507
(Catalog# : 16122732, Cas# :
159182-43-1
)
L-755,507 is characterized as a potent and selective 3 adrenergic receptor partial ag
LY333531
(Catalog# : 16122722, Cas# :
169939-93-9
)
LY333531 is a -specific protein kinase C inhibitor. It competitively and reversibly i
Lenalidomide hydrochloride
(Catalog# : 6111410, Cas# :
1243329-97-6
)
Lenalidomide (Revlimid, CC-5013) is a TNF- secretion inhibitor with IC50 of 13 nM
Lenalidomide hemihydrate
(Catalog# : 6111409, Cas# :
847871-99-2
)
Lenalidomide (Revlimid, CC-5013) is a TNF- secretion inhibitor with IC50 of 13 nM.Len
LOXO-101
(Catalog# : 61123, Cas# :
1223405-08-0
)
LOXO-101 is an oral potent and selective ATP-competitive inhibitor of tropomyosin rec
LPA2 antagonist 1
(Catalog# : 61120, Cas# :
1017606-66-4
)
LPA2 antagonist 1 is a selective inhibitor of LPA2 activity in with IC50 17 nM in vit
Liproxstatin-1
(Catalog# : 6111018, Cas# :
950455-15-9
)
Liproxstatin-1
Lasmiditan
(Catalog# : 6111006, Cas# :
439239-90-4
)
Lasmiditan (COL-144; LY573144) is a high-affinity, highly selective 5-HT1F receptor a
Lasmiditan hydrochloride
(Catalog# : 6111005, Cas# :
613677-28-4
)
Lasmiditan (COL-144; LY573144) is a high-affinity, highly selective 5-HT1F receptor a
Litronesib
(Catalog# : 611944, Cas# :
910634-41-2
)
Litronesib is a selective, allosteric inhibitor of Eg5, which may result in mitotic d
LY 303511 hydrochloride
(Catalog# : 611819)
LY303511 Hcl, an inactive analogue of LY294002, is a mTOR inhibitor that did not inhi
LY 303511
(Catalog# : 611818, Cas# :
154447-38-8
)
LY303511, an inactive analogue of LY294002, is a mTOR inhibitor that did not inhibit
LY3023414
(Catalog# : 611808, Cas# :
1386874-06-1
)
LY3023414 is an oral ATP competitive inhibitor of the class I PI3K isoforms, mTOR and
Lifitegrast
(Catalog# : 16071412, Cas# :
1025967-78-5
)
Lifitegrast, also known as SAR-1118, is an LFA-1 antagonist intended for the treatmen
Lonafarnib
(Catalog# : 16071008, Cas# :
193275-84-2
)
Lonafarnib is a farnesyl transferase inhibitor. Structurely, it is also a synthetic t
LJI308
(Catalog# : 16070904, Cas# :
1627709-94-7
)
LJI308 is a potent, and pan-RSK(p90 ribosomal S6 kinase) inhibitor withIC50of 6 nM, 4
LJH685
(Catalog# : 16070903, Cas# :
1627710-50-2
)
LJH685 is a potent pan-RSKinhibitor withIC50of 6 nM, 5 nM and 4 nM for RSK1, RSK2, an
LX1606 (Hippurate)
(Catalog# : 16062301, Cas# :
1137608-69-5
)
LX1606 is an orally bioavailable, small-molecule, tryptophan hydroxylase (TPH) inhibi
Lumateperone(ITI-007)
(Catalog# : 632801, Cas# :
313368-91-1
)
ITI-007 is an investigational atypical antipsychotic which is currently under develop
LGD-4033(Ligandrol)
(Catalog# : 030907, Cas# :
1165910-22-4
)
LGD-4033, also known as VK5211 and Ligandrol, is an investigational selective androge
LY-379268
(Catalog# : 011904, Cas# :
191471-52-0
)
Coming soon!
Lefamulin acetate
(Catalog# : 011808, Cas# :
1350636-82-6
)
Coming soon!
Lefamulin
(Catalog# : 011807, Cas# :
1061337-51-6
)
Coming soon!
L-165041
(Catalog# : 011316, Cas# :
79558-09-1
)
Coming soon!
Linsitinib
(Catalog# : 010819, Cas# :
867160-71-2
)
Linsitinib is highly potent, orally efficacious and highly selective, dual ATP-compet
Lestaurtinib
(Catalog# : 010815, Cas# :
111358-88-4
)
Lesraurtinib is an orally bioavailable indolocarbazole derivative with antineoplastic
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
Zelasudil
(Catalog# : 24014, Cas# :
2365193-22-0
)
Zelasudil is a potent, highly selective and orally-active inhibitor that targets Rho-
Ziftomenib ( KO-539 )
(Catalog# : 24013, Cas# :
2134675-36-6
)
Ziftomenib is an oral, potent, and selective small molecule inhibitor that targets th
Zunsemetinib
(Catalog# : 24012, Cas# :
1640282-42-3
)
Zunsemetinib is an investigational oral mitogen-activated protein kinase-activated pr
Zongertinib
(Catalog# : 24011, Cas# :
2728667-27-2
)
Zongertinib [BI 1810631] is a human epidermal growth factor receptor 2 (HER2) inhibit
Zasocitinib
(Catalog# : 24010, Cas# :
2272904-53-5
)
Zasocitinib is under development for the treatment of moderate to severe plaque psori
RNK-05047
(Catalog# : 24008, Cas# :
2503036-46-0
)
RNK-05047 is a PROTAC degrader of BRD4 which displays significant tumor growth inhibi
Asengeprast (FT011)
(Catalog# : 24009, Cas# :
1001288-58-9
)
Asengeprast (FT011) is an anti-fibrotic agent thatreduces mRNA expression of collagen
ERAS-801 ( JGK-068S )
(Catalog# : 20635, Cas# :
2490431-16-6
)
ERAS-801 ( JGK-068S ) is a potent EGFR inhibitor.
T-1095
(Catalog# : 24004, Cas# :
209746-59-8
)
T-1095 is a potent and selective inhibitor of Na+-glucose cotransporters (SGLTs).
NVL-655 ( ALK-IN-27 )
(Catalog# : 24003, Cas# :
2739866-40-9
)
NVL-655 is a novel, brain-penetrant, ALK-selective inhibitor that was designed to add