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Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
Building Blocks
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
Building Blocks
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
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Name Index M
MK-1064
(Catalog# : 16123054, Cas# :
1207253-08-4
)
MK-1064 is a potent, selective and orally active Orexin OX2 Receptor Antagonist for p
MI-503
(Catalog# : 178908, Cas# :
1857417-13-0
)
MI-503 is a potent and selective Menin-MLL inhibitor with IC50 of 14.7 nM. It shows p
Merestinib (LY2801653)
(Catalog# : 178905, Cas# :
1206799-15-6
)
Merestinib, also known as LY2801653, is a n orally available, small molecule inhibito
Miglustat hydrochloride
(Catalog# : 2017824, Cas# :
210110-90-0
)
Miglustat, also known as OGT 918, is a drug developed by Actelion and is used prima
MK-0812
(Catalog# : 2017080111, Cas# :
624733-88-6
)
MK-0812 is a potent and selective CCR2 antagonist. Chemokine (C-C motif) receptor 2 (
MONASCIN
(Catalog# : 201708015, Cas# :
21516-68-7
)
It is a potent inhibitor of car inogenesis measured against chemical- or UV-initiated
Mephenytoin
(Catalog# : 174161, Cas# :
50-12-4
)
Mephenytoin(CAS 50-12-4) is a hydantoin, used as an anticonvulsant.Mephenytoin(CAS 50
MT-DADMe-ImmA
(Catalog# : 703301, Cas# :
653592-04-2
)
Methylthio-DADMe-immucillin-A (MT-DADMe-ImmA) is an 86-pm inhibitor of human 5-methyl
MI-463
(Catalog# : 17031006, Cas# :
1628317-18-9
)
MI-463 is a potent inhibitor of Menin-MLL interaction with an IC50 value of 15.3 nM
ML-098
(Catalog# : 17030910, Cas# :
878978-76-8
)
ML-098, also known as CID-7345532, is an activator of the GTP-binding protein Rab7 (E
ML-265
(Catalog# : 17030804, Cas# :
1221186-53-3
)
ML265 is a potent PKM2 activator induces tetramerization and reduces tumor formation
MN-64
(Catalog# : 17030717, Cas# :
92831-11-3
)
MN-64 is a potent and selective inhibitor of Tankyrase 1 and 2 (IC50 = 6 and 72 nM, r
ML241
(Catalog# : 17030714, Cas# :
1346528-06-0
)
ML241 is a potent and selective inhibitors of p97 ATPase. ML241 inhibit p97 ATPase wi
ML348
(Catalog# : 17030712, Cas# :
899713-86-1
)
ML348, also known as CID 3238952; SID 160654487, is a reversible LYPLA1 inhibitor wit
Mavoglurant
(Catalog# : 17030612, Cas# :
543906-09-8
)
Mavoglurant, aslo known as AFQ056, is an experimental drug candidate for the treatmen
MMAF (Monomethyl auristatin F)
(Catalog# : 17030611, Cas# :
745017-94-1
)
Monomethyl auristatin F (MMAF) is a synthetic antineoplastic agent. It is part of som
Merimepodib
(Catalog# : 17030308, Cas# :
198821-22-6
)
Merimepodib, also known as VX-497, is orally bioavailable IMPDH inhibitor, which inhi
ML-264
(Catalog# : 17030302, Cas# :
1550008-55-3
)
ML-264 is a Krppel-like factor 5 (KLF5) inhibitor That Potently Inhibits Growth of Co
MK-8245
(Catalog# : 17030109, Cas# :
1030612-90-8
)
MK-8245 is a potent, liver-targeted SCD inhibitor with preclinical antidiabetic and a
MLN-1117
(Catalog# : 17030101, Cas# :
1268454-23-4
)
Serabelisib (also known as MLN1117, INK1117, and TAK-117) is an orally bioavailable i
ML-281
(Catalog# : 17022811, Cas# :
1404437-62-2
)
ML-281 is a potent ans selective STK33 inhibitor (IC50 = 14 nM). ML281 showed low nan
Maraviroc
(Catalog# : 17022804, Cas# :
376348-65-1
)
Maraviroc (UK-427857; Selzentry; Celsentri) is a selective CCR5 antagonist (IC50= 6.4
MMAE (Monomethyl auristatin E)
(Catalog# : 17022403, Cas# :
474645-27-7
)
MMAE, also known as Monomethyl auristatin E, is a synthetic antineoplastic agent. Bec
Monastrol
(Catalog# : 17021322, Cas# :
329689-23-8
)
Monastrol is a cell-permeable small molecule inhibitor of kinesin-5(KIF11) which is
MS049
(Catalog# : 17021313, Cas# :
1502816-23-0
)
MS049 is a potent and selective inhibitor of PRMT4 and PRMT6 with IC50s of 34 nM
Miransertib(ARQ 092)
(Catalog# : 17021301, Cas# :
1313883-00-9
)
ARQ 092 is a novel, orally bioavailable and selective AKT pathway inhibitor exhibit
MT-DADMe-ImmA(MTDIA HCl)
(Catalog# : 712101, Cas# :
1399840-35-7
)
Methylthio-DADMe-immucillin-A (MT-DADMe-ImmA) is an 86-pm inhibitor of human 5-methyl
7-Methyl-7H-pyrrolo[2,3-d]pyriMidin-4-aMine
(Catalog# : 17011908, Cas# :
7752-54-7
)
7-Methyl-7H-pyrrolo[2,3-d]pyriMidin-4-aMine
ML-7
(Catalog# : 17011107, Cas# :
110448-33-4
)
ML-7 is an inhibitor of smooth muscle myosin light chain kinase (MLCK) with a Ki
MX69
(Catalog# : 17011105, Cas# :
1005264-47-0
)
MX69 is a MDM2/XIAP inhibitor, used for cancer treatment.
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
PLX8394
(Catalog# : 20613, Cas# :
1393466-87-9
)
PLX8394 is an orally bioavailable inhibitor of serine/threonine-protein kinase B-raf
Zelasudil
(Catalog# : 24014, Cas# :
2365193-22-0
)
Zelasudil is a potent, highly selective and orally-active inhibitor that targets Rho-
Ziftomenib ( KO-539 )
(Catalog# : 24013, Cas# :
2134675-36-6
)
Ziftomenib is an oral, potent, and selective small molecule inhibitor that targets th
Zunsemetinib
(Catalog# : 24012, Cas# :
1640282-42-3
)
Zunsemetinib is an investigational oral mitogen-activated protein kinase-activated pr
Zongertinib
(Catalog# : 24011, Cas# :
2728667-27-2
)
Zongertinib [BI 1810631] is a human epidermal growth factor receptor 2 (HER2) inhibit
Zasocitinib
(Catalog# : 24010, Cas# :
2272904-53-5
)
Zasocitinib is under development for the treatment of moderate to severe plaque psori
RNK-05047
(Catalog# : 24008, Cas# :
2503036-46-0
)
RNK-05047 is a PROTAC degrader of BRD4 which displays significant tumor growth inhibi
Asengeprast (FT011)
(Catalog# : 24009, Cas# :
1001288-58-9
)
Asengeprast (FT011) is an anti-fibrotic agent thatreduces mRNA expression of collagen
ERAS-801 ( JGK-068S )
(Catalog# : 20635, Cas# :
2490431-16-6
)
ERAS-801 ( JGK-068S ) is a potent EGFR inhibitor.
T-1095
(Catalog# : 24004, Cas# :
209746-59-8
)
T-1095 is a potent and selective inhibitor of Na+-glucose cotransporters (SGLTs).