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Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
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Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
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Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
Building Blocks
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
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Other Azoles
Other Heterocycles
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Name Index P
PF-9366
(Catalog# : 184107, Cas# :
72882-78-1
)
PF-9366 is a novel inhibitor of human methionine adenosyltransferase 2A (Mat2A), the
PFI-2 hydrochloride
(Catalog# : 184106, Cas# :
1627607-87-7
)
PFI-2 is a potent inhibitor of SETD7 with IC50 2 nM and 1000-fold selectivity over ot
PCI-29732
(Catalog# : 184101, Cas# :
330786-25-9
)
PCI-29732 is a BTK inhibitor. It acts by blocking B cell antigen receptor (BCR)-media
PF-0684000
(Catalog# : 184318, Cas# :
198474-05-4
)
PF-0684000, also known as EOS200271, is potent IDO-1 inhibitor (IC50 0.15 μM). PF-06
PF-06409577
(Catalog# : 18434, Cas# :
1467057-23-3
)
PF-06409577 is a potent and selective activator of 5′ adenosine monophosphate-activ
PhTx-74盐酸盐
(Catalog# : 18429, Cas# :
1227301-51-0
)
蜂毒毒素-74,也称为PhTx-74,是一种人工合成的寄生蜂毒素-4,3,3。PhTX
PRN-1371
(Catalog# : 17101614, Cas# :
1802929-43-6
)
PRN-1371 is a covalent, irreversible, highly selective FGFR1, 2, 3 and 4 inhibitor. P
PF-5006739
(Catalog# : 17101612, Cas# :
1293395-67-1
)
PF-5006739 is a Potent CK1δ/ε inhibitor. PF-5006739 attenuates opioid drug-seeking
PF-04628935
(Catalog# : 17101611, Cas# :
1383719-97-8
)
PF-04628935 is a potent antagonist/inverse agonist of the ghrelin receptor, growth ho
PIM447
(Catalog# : 1710134, Cas# :
1210608-43-7
)
PIM447, also known as LGH447, is a potent Moloney murine leukemia (PIM) 1, 2, and 3 k
PF-562271 HCl
(Catalog# : 179302, Cas# :
939791-41-0
)
PF-562271, also known as PF-562,271 and PF-271, is an orally bioavailable small molec
Pemafibrate
(Catalog# : 179221, Cas# :
848259-27-8
)
(1)Pemafibrate, also known as K-877 and (R)-K 13675, is a PPAR alpha agonist. (R)-K-1
Pyridostatin TFA salt
(Catalog# : 1791517, Cas# :
179474-81-8
)
Pyridostatin stabilizes G-quadruplexes (G4s) in cells and elicits a DNA damage respon
Prucalopride Succinate
(Catalog# : 1791516, Cas# :
179474-85-2
)
Prucalopride, also known as R-108512, is a selective, high affinity serotonin (5-HT4)
PRT4165
(Catalog# : 1791515, Cas# :
31083-55-3
)
PRT4165 is a small molecule inhibitor of polycomb repressive complex 1, which inhibit
Pramipexole HCl
(Catalog# : 1791510, Cas# :
104632-25-9
)
Pramipexole Dihydrochloride is an agonist of the Gαi-linked dopamine receptors D2, D
PF-06281355
(Catalog# : 1791312, Cas# :
1435467-38-1
)
PF-06281355, also known as PF-1355, is an orally available, selective and potent mech
Puromycin Aminonucleoside
(Catalog# : 1791310, Cas# :
58-60-6
)
Puromycin Aminonucleoside, also known as PAN, NSC3056, is useful in the study of huma
P7C3-OMe
(Catalog# : 179116, Cas# :
1235481-43-2
)
P7C3-OMe, also known as (R)-P7C3-OMe, is an analogue of P7C3 and P3C3-A20. P7C3 Atten
PF-CBP1 free base
(Catalog# : 179113, Cas# :
1962928-21-7
)
PF-CBP1, also known as PF-06670910, is potent and highly-selective inhibitor of the b
PF-CBP1 HCl
(Catalog# : 179112, Cas# :
2070014-93-4
)
PF-CBP1, also known as PF-06670910, is potent and highly-selective inhibitor of the b
PF-06650833
(Catalog# : 17988, Cas# :
1817626-54-2
)
PF-06650833 is an inhibitor of Interleukin-1 receptor associated kinase 4 (IRAK4). RA
Prexasertib mesylate
(Catalog# : 17986, Cas# :
1234015-55-4
)
Prexasertib, also known as LY2606368, is a potent and selective Chk1/Chk2 inhibitor.
PF-01247324
(Catalog# : 1781102, Cas# :
875051-72-2
)
PF-01247324 is a novel selective and orally bioavailable Nav 1.8 channel blocker, att
PD166866
(Catalog# : 178814, Cas# :
192705-79-6
)
PD166866 has clear antiproliferative effects.
Perindoprilat
(Catalog# : 2017829, Cas# :
95153-31-4
)
Perindoprilat is a potent and long-acting angiotensin converting enzyme inhibitor, ca
PF 04929113
(Catalog# : 2017826, Cas# :
908115-27-5
)
PF-04929113, also known as SNX-5422; is a synthetic prodrug targeting the human heat-
Palonosetron
(Catalog# : 2017080119, Cas# :
135729-61-2
)
Palonosetron is a 5-HT3 antagonist used in the prevention and treatment of chemothera
Patent blue violet purified
(Catalog# : 2017080117, Cas# :
68238-36-8
)
Purification of patent blue purple and isosulfan blue, it is a kind of dye and pigmen
Propamocarb hydrochloride
(Catalog# : 2017080115, Cas# :
25606-41-1
)
Propamocarb hydrochloride is an efficient, broad-spectrum, carbamate fungicide safe.
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
PLX8394
(Catalog# : 20613, Cas# :
1393466-87-9
)
PLX8394 is an orally bioavailable inhibitor of serine/threonine-protein kinase B-raf
Zelasudil
(Catalog# : 24014, Cas# :
2365193-22-0
)
Zelasudil is a potent, highly selective and orally-active inhibitor that targets Rho-
Ziftomenib ( KO-539 )
(Catalog# : 24013, Cas# :
2134675-36-6
)
Ziftomenib is an oral, potent, and selective small molecule inhibitor that targets th
Zunsemetinib
(Catalog# : 24012, Cas# :
1640282-42-3
)
Zunsemetinib is an investigational oral mitogen-activated protein kinase-activated pr
Zongertinib
(Catalog# : 24011, Cas# :
2728667-27-2
)
Zongertinib [BI 1810631] is a human epidermal growth factor receptor 2 (HER2) inhibit
Zasocitinib
(Catalog# : 24010, Cas# :
2272904-53-5
)
Zasocitinib is under development for the treatment of moderate to severe plaque psori
RNK-05047
(Catalog# : 24008, Cas# :
2503036-46-0
)
RNK-05047 is a PROTAC degrader of BRD4 which displays significant tumor growth inhibi
Asengeprast (FT011)
(Catalog# : 24009, Cas# :
1001288-58-9
)
Asengeprast (FT011) is an anti-fibrotic agent thatreduces mRNA expression of collagen
ERAS-801 ( JGK-068S )
(Catalog# : 20635, Cas# :
2490431-16-6
)
ERAS-801 ( JGK-068S ) is a potent EGFR inhibitor.
T-1095
(Catalog# : 24004, Cas# :
209746-59-8
)
T-1095 is a potent and selective inhibitor of Na+-glucose cotransporters (SGLTs).